Results 141 to 150 of about 6,236,563 (298)

PROFILES AND PREFERENCES OF ON-LINE MILLENIAL SHOPPERS IN BULGARIA

open access: yesEconomic Review, 2014
This research seeks to develop a better understanding of the factors affecting on-line purchasing behavior among Generation Y (Gen Y) consumers in Bulgaria. Also called millenials and born between the mid-1970s and late 1990s, this generation is especially active online and will be a dominant influence shaping e-commerce.
Loubeau, Patricia R.   +2 more
openaire   +5 more sources

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

open access: yesMolecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka   +9 more
wiley   +1 more source

Analysis of Coronal Line Profiles Final Report [PDF]

open access: yes, 1969
Fabry-Perot interferometer measurements of emission line profiles in solar ...
Deuel, R. W.
core  

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

open access: yesMolecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu   +13 more
wiley   +1 more source

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola   +11 more
wiley   +1 more source

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

open access: yesMolecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim   +3 more
wiley   +1 more source

PAK1 activation drives divergent resistance mechanisms to aromatase inhibition and tamoxifen in a luminal: A breast cancer model

open access: yesMolecular Oncology, EarlyView.
Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller   +10 more
wiley   +1 more source

Deconvolution of the Spectral Line Profiles for the Plasma Temperature Estimation

open access: yes
Deconvolution of the spectral line profiles for the plasma temperature ...
Zorina, Natalia   +2 more
core  

line upon line percussion: A Guest Artist Recital [PDF]

open access: yes, 2011
This is the program for the guest artist recital of the group line upon line percussion, featuring Adam Bedell, Cullen Faulk, and Matthew Teodori. This recital took place on September 26, 2011, in the W.
line upon line percussion
core  

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