Results 121 to 130 of about 6,236,563 (298)
CO Line Profiles in Accreting Ices
The Astrophysical JournalWe investigate how the infrared absorption profile of the solid-state CO stretching mode reflects the chemical and structural environments produced during ice growth under astrophysically relevant conditions. Using two complementary deposition protocols,
Rashida Aslam +7 more
doaj +1 more source
Molecular Oncology, EarlyView.In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge +17 more
wiley +1 more source
Molecular Oncology, EarlyView.In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera +11 more
wiley +1 more source
Asymmetrical shape of the near-infrared K 4p–5s doublet perturbed by He and H2
Astronomy & AstrophysicsThe goal of this paper is to provide an exhaustive study of the K 4p–5s doublet at 1.243/1.252 μm perturbed by He and H2 under the physical conditions of brown dwarfs.
Allard N. F., Kielkopf J. F.
doaj +1 more source
Molecular Oncology, EarlyView.RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner +14 more
wiley +1 more source
Molecular Oncology, EarlyView.Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary +1 more
wiley +1 more source
The Shape of Coronal-Line Profiles.
The Astrophysical Journal, 1964 Line profiles are distorted from Gaussian in a characteristic manner if the matter is undergoing either harmonic oscillation or radial flow in cylindrical structures. They are distorted in the opposite sense by a distribution of temperatures along the line of sight.
openaire +1 more source
Molecular Oncology, EarlyView.This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source
The coronal line region of active galactic nuclei
Frontiers in Astronomy and Space SciencesForbidden coronal lines has traditionally called the attention due to the high-energy photons required for their production (IP >100 eV, where IP is the ionisation potential of the transitions that originate the line).
Alberto Rodríguez-Ardila +3 more
doaj +1 more source
Molecular Oncology, EarlyView.Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura +19 more
wiley +1 more source