Results 31 to 40 of about 7,732,330 (302)

Studies of Growth Regulation in a Neuroendocrine Cell Line [PDF]

open access: yesActa Oncologica, 1993
Studies of growth-regulation of neuroendocrine cells have been hampered by a lack of suitable in vitro models. We established and have maintained a functioning human pancreatic carcinoid cell (BON) line. BON cells synthesize and secrete several growth factors.
C M, Townsend   +2 more
openaire   +2 more sources

Context‐specific regulation of LINE‐1 [PDF]

open access: yesGenes to Cells, 2007
The present study was conducted to evaluate the contextual specificity of long interspersed nuclear element‐1 (LINE‐1 or L1) activation by cellular stress and the role of the aryl hydrocarbon receptor (AHR) transcription factor and oxidative stress in the gene activation response.
Ivo, Teneng   +2 more
openaire   +2 more sources

Electricity network regulation in the EU : The challenges ahead‎ for transmission and distribution

open access: yes, 2018
The UK model of incentive regulation of power grids was at one time the most advanced, and elements of it were adopted throughout the EU. This model worked well, particularly in the context of limited investment and innovation, a single and strong ...

core   +1 more source

Regulation of Telomerase Activity in Immortal Cell Lines [PDF]

open access: yesMolecular and Cellular Biology, 1996
Telomerase is a ribonucleoprotein whose activity has been detected in germ line cells, immortal cells, and most cancer cells. Except in stem cells, which have a low level of telomerase activity, its activity is absent from normal somatic tissues. Understanding the regulation of telomerase activity is critical for the development of potential tools for ...
S E, Holt, W E, Wright, J W, Shay
openaire   +2 more sources

RNA sensor MDA5 suppresses LINE-1 retrotransposition by regulating the promoter activity of LINE-1 5′-UTR

open access: yesMobile DNA, 2022
Background Type 1 long interspersed elements, or LINE-1, are the only retroelements that replicate autonomously in human cells. The retrotransposition process of LINE-1 can trigger the activation of the innate immune system and has been proposed to play ...
Jiaxiu Yan   +8 more
doaj   +1 more source

Phosphorus-Solubilizing Bacteria Enhance Cadmium Immobilization and Gene Expression in Wheat Roots to Reduce Cadmium Uptake

open access: yesPlants
The application of phosphorus-solubilizing bacteria is an effective method for increasing the available phosphorus content and inhibiting wheat uptake of heavy metals.
Delong Kan   +3 more
doaj   +1 more source

The importance of distinguishing between the different eating disorders (sub)types when assessing emotion regulation strategies [PDF]

open access: yes, 2014
People with eating disorders (ED) have difficulties regulating their emotions adaptively. Little is known about differences and similarities between different types of ED and how these regulation difficulties relate to other emotional problems.
Stress and self-regulation   +4 more
core   +1 more source

Ovarian Sex Cord Stromal Tumors in Children and Adolescents—The European Standard Clinical Practice Recommendations

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT As part of the European Cooperative Study Group for Paediatric Rare Tumours initiative, we developed standard clinical practice guidelines for ovarian sex cord stromal tumors, based on comprehensive national and international cohort analyses, literature review, and a final expert consensus conference.
Dominik T. Schneider   +15 more
wiley   +1 more source

Establishment of a human embryonic stem cell line, WAe009-A-99, with constitutive expression of the dCas9-p300 fusion protein

open access: yesStem Cell Research, 2023
CRISPR/Cas9-based transcriptional regulation systems can induce the site-specific activation or repression of endogenous genes. p300 is a transcriptional co-activator that functions as a histone acetyltransferase that regulates gene transcription via ...
Eun-Hye Kang   +6 more
doaj   +1 more source

Survival After Hematopoietic Stem Cell Transplantation in Diamond–Blackfan Anemia Syndrome: The Role of Iron Overload—A Systematic Review

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT We assessed the effect of iron overload (IO) on mortality and complications following hematopoietic stem cell transplantation (HSCT) in patients with Diamond–Blackfan anemia syndrome (DBAS) in a systematic review of individual participant data and cohort data from observational studies.
Geoffrey Z. L. Kuppens   +6 more
wiley   +1 more source

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