Results 81 to 90 of about 7,732,330 (302)

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

Tasmanian main line railway [cartographic material].

open access: yes, 1880
Map showing the main railway line from Hobart to Launceston in red, the Mersey, Deloraine, Launceston and Western Railway in black and the projected line from Bridgewater in a broken red line.; Australian Encyclopedia, 6th ed., v. 7, p.

core  

The Financial Inclusion Trilemma

open access: yes
This page contains the data necessary to replicate the results of "The Financial Inclusion Trilemma" by Adam J. Levitin, published in the Yale Journal on Regulation (2024)
Journal on Regulation, Yale
core   +1 more source

LSD: a Line Segment Detector [PDF]

open access: yes, 2012
LSD is a linear-time Line Segment Detector giving subpixel accurate results. It is designed to work on any digital image without parameter tuning. It controls its own number of false detections: On average, one false alarms is allowed per image.
Randall, Gregory   +7 more
core   +1 more source

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

open access: yesFEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang   +4 more
wiley   +1 more source

Human liposarcoma cell line, SW872, secretes cholesteryl ester transfer protein in response to cholesterol

open access: yesJournal of Lipid Research, 1996
Cholesteryl ester transfer protein (CETP) mediates the exchange of phospholipids and neutral lipids between the plasma lipoproteins, and plays an important role in high density lipoprotein (HDL) metabolism.
M A Richardson   +4 more
doaj   +1 more source

Discretionary Investing by ‘Passive’ S&P 500 Funds

open access: yes
This page contains the code and data necessary to replicate the results of "Discretionary Investing by ‘Passive’ S&P 500 Funds" by Peter Molk & Adriana Z. Robertson, published in the Yale Journal on Regulation (2024)
Journal on Regulation, Yale
core   +1 more source

The Specifics of Legal Regulation of Relations in the Field of Transportation of Oil and Gas by Trunk-Line

open access: yes, 2018
Kramar, R., Kovaliv, M., Yesimov, S., & Skrynkovskyy, R. (2018). The Specifics of Legal Regulation of Relations in the Field of Transportation of Oil and Gas by Trunk-Line.
Myroslav Kovaliv (4912261)   +3 more
core   +1 more source

Electricity Network Investment and Regulation for a Low Carbon Future [PDF]

open access: yes, 2007
The requirement for significantly higher electricity network investment in the UK seems certain as the capacity of distributed generation and large scale renewables increases on the system.

core   +2 more sources

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

open access: yesFEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta   +3 more
wiley   +1 more source

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