Results 101 to 110 of about 10,265,072 (333)

A Rapid Convergent Low Complexity Interference Alignment Algorithm for Wireless Sensor Networks

open access: yesSensors, 2015
Interference alignment (IA) is a novel technique that can effectively eliminate the interference and approach the sum capacity of wireless sensor networks (WSNs) when the signal-to-noise ratio (SNR) is high, by casting the desired signal and interference
Lihui Jiang   +4 more
doaj   +1 more source

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

open access: yesMolecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla   +10 more
wiley   +1 more source

A Search for Nitrogen Enriched Quasars in the Sloan Digital Sky Survey Early Data Release

open access: yes, 2004
A search for nitrogen-rich quasars in the Sloan Digital Sky Survey Early Data Release (SDSS EDR) catalog has yielded 16 candidates, including five with very prominent emission, but no cases with nitrogen emission as strong as in Q0353-383.
Barbaro G.   +7 more
core   +2 more sources

Therapeutic strategies for MMAE‐resistant bladder cancer through DPP4 inhibition

open access: yesMolecular Oncology, EarlyView.
We established monomethyl auristatin E (MMAE)‐resistant bladder cancer (BC) cell lines by exposure to progressively increasing concentrations of MMAE in vitro. RNA sequencing showed DPP4 expression was increased in MMAE‐resistant BC cells. Both si‐DPP4 and the DPP4 inhibitor sitagliptin suppressed the viability of MMAE‐resistant BC cells.
Gang Li   +10 more
wiley   +1 more source

Recurrent cancer‐associated ERBB4 mutations are transforming and confer resistance to targeted therapies

open access: yesMolecular Oncology, EarlyView.
We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala   +15 more
wiley   +1 more source

An S-Hybridization Technique Using Two-Directional Optimization

open access: yesAxioms
In this paper, we study a recently established s-hybrid approach for generating gradient descent methods for solving optimization tasks. We present an s-hybrid variant of the accelerated double-direction method.
Vladimir Rakočević   +1 more
doaj   +1 more source

Combining antibody conjugates with cytotoxic and immune‐stimulating payloads maximizes anti‐cancer activity

open access: yesMolecular Oncology, EarlyView.
Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang   +3 more
wiley   +1 more source

A novel three-term conjugate gradient approach for deep neural network training [PDF]

open access: yesIranian Journal of Numerical Analysis and Optimization
This paper presents a new three-term conjugate gradient (CG) method for large-scale unconstrained optimization, with application to training deep neural networks.
Faeze Sadat Hosseini-Mighan, Ali Ashrafi
doaj   +1 more source

SEARCH FOR GRAVITATIONALLY REDSHIFTED 2.2 MEV LINE FROM 4U 1820-30 [PDF]

open access: yes, 2007
We have analyzed 1.7 Ms of the INTEGRAL data of the Low Mass X-Ray Binary (LMXB) 4U 1820-30 and searched for the redshifted 2.2 MeV neutron capture gamma-ray line.
Boggs, Steven E.   +3 more
core  

Tumor mutational burden as a determinant of metastatic dissemination patterns

open access: yesMolecular Oncology, EarlyView.
This study performed a comprehensive analysis of genomic data to elucidate whether metastasis in certain organs share genetic characteristics regardless of cancer type. No robust mutational patterns were identified across different metastatic locations and cancer types.
Eduardo Candeal   +4 more
wiley   +1 more source

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