Results 61 to 70 of about 19,173 (257)

Nutrient/TOR signaling controls adipose mitochondrial transcription factor A (TFAM) to regulate organismal growth in Drosophila

open access: yesFEBS Letters, EarlyView.
Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas   +4 more
wiley   +1 more source

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

open access: yesFEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt   +8 more
wiley   +1 more source

Combining ability analysis and estimation of heterosis for agronomic and oil parameters in sunflower

open access: yesElectronic Journal of Plant Breeding
Combining ability of nine sunflower inbreds (four cytoplasmic male sterile lines and five restorers) was tested in line x tester mating design. The material including parents and cross combinations were evaluated for nine agro-biochemical parameters. The
V. Kaila
doaj   +1 more source

Combining ability analysis for yield and yield components in sesame (Sesamum indicum L.) [PDF]

open access: yesElectronic Journal of Plant Breeding, 2015
Combining ability for eleven characters was studied in sesame using 10 lines viz., ES-246, AT-24, SPS-19, BAVJ-1, TNAU-2, Kalyanpur-2, Mota Liliya-1, Ingorola-7, SI-968 and Timbi-3 as females and 4 testers RT-125, Guj.Til-1, Guj.Til-2 and Guj.Til-10 as ...
Joshi, H. K., Patel, S. R., Pathak, A. R. and Patel, R. K.
doaj  

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

open access: yesFEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang   +2 more
wiley   +1 more source

Estimation of heterosis in pearl millet [Pennisetum glaucum (L.)] for yield and quality traits

open access: yesElectronic Journal of Plant Breeding, 2016
Five CMS lines were crossed with nine testers in a line x tester design to study the extent of heterosis in pearl millet for yield and quality traits. Heterosis was observed in both directions for most of the characters.
K.U. Nandaniya   +2 more
doaj   +1 more source

The anther-culture response of triticale line x tester progenies.

open access: yesCellular & molecular biology letters, 2004
Seven triticale cultivars (Ampiac, Aubrac, Trinidad, Ticino, Lamberto, Pronto and Prado) and their F1 hybrids obtained after crossing in a line x tester scheme were examined with respect to their androgenetic effectiveness. The embryo induction rate (number of embryos per 100 anthers), green plant regeneration rate (number of green plantlets per 100 ...
Karol, Marciniak   +3 more
openaire   +1 more source

Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network

open access: yesFEBS Letters, EarlyView.
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley   +1 more source

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

open access: yesFEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri   +5 more
wiley   +1 more source

Gene action and combining ability analyses to develop NPT based rice hybrids in Chhattisgarh plains [PDF]

open access: yesElectronic Journal of Plant Breeding, 2015
Combining ability in New Plant Type (NPT) lines of rice for hybrid rice breeding programme has been carried out in line x tester mating design involving 3 CMS lines and 6 testers.
Ishu Kumar Khute, Satyapal Singh, Parmeshwar Sahu and Deepak Sharma
doaj  

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