Results 251 to 260 of about 503,355 (348)

Rictor Ameliorates Acute Antibody‐Mediated Rejection Following Kidney Transplantation by Suppressing Macrophage M1 Polarization Through p65‐NLRP3 Axis

Advanced Science, EarlyView.
This study elucidates the critical role of Rictor in macrophage activation in acute antibody‐mediated rejection (ABMR). Rictor increases K48‐linked ubiquitination of p65 by upregulating E3 ubiquitin ligase SOCS1, inhibiting transcriptional levels of NLRP3 and inflammasome activation.
Bin Ni, Chengcheng Yang, Junqi Zhang, Zhou Hang, Ming Zheng, Dengyuan Feng, Qinghuan Shen, Jinxu Miao, Xulin Sun, Li Sun, Baixin Shen, Min Gu, Zijie Wang   +12 more
wiley   +1 more source

A haplotype-resolved chromosomal reference genome for the porcini mushroom Boletus edulis. [PDF]

G3 (Bethesda)
Brejon Lamartinière E, Tremble K, Dentinger BTM, Dasmahapatra KK, Hoffman JI.   +4 more
europepmc   +1 more source

Direct In Vivo Cell Lineage Analysis in the Retrorsine and 2AAF Models of Liver Injury after Genetic Labeling in Adult and Newborn Rats

, 2009
Virginie Pichard, Dominique Aubert, Nicolas Ferry   +2 more
openalex   +2 more sources

Hosts and Commensal Bacteria Synergistically Antagonize Opportunistic Pathogens at the Single‐Cell Resolution

Advanced Science, EarlyView.
In the tripartite‐species model, Drosophila larvae stimulate lactate production through excreting digestion enzymes. S. marcescens population senses a cue of lactate and tends to diverge into virulent and reduced virulence subclusters with remarkable heterogeneity to metabolize carbon metabolism and counter colonization resistance, giving a fitness ...
Sheng Zhang, Ziguang Wang, Anqi Liu, Jinshu Li, Jingjing Zhuang, Xiaowen Ji, Paul I. Mulama, Maoye Li, Haiqun Cao, Eng‐King Tan, Wei Liu   +10 more
wiley   +1 more source

Genomic insights into the population structure, antimicrobial resistance, and virulence of <i>Brachyspira hyodysenteriae</i> from diverse geographical regions. [PDF]

Microbiol Spectr
Hakimi M, Ye F, Saxena A, Hu X, Shen H, Elankumaran P, Stinman CC, Macedo N, Sahin O, Burrough ER, Li G.   +10 more
europepmc   +1 more source

Puumala hantavirus and Myodes glareolus in northern Europe: no evidence of co-divergence between genetic lineages of virus and host

, 2010
Kirill Nemirov, Herwig Leirs, Åke Lundkvist, Gert E. Olsson   +3 more
openalex   +1 more source

The Role of MCPIP1 in Macrophage Polarization and Cardiac Function Post‐Myocardial Infarction

Advanced Science, EarlyView.
Following myocardial infarction, MCPIP1 deficiency in macrophages triggers ferroptosis, driving proinflammatory M1 dominance over reparative M2 phenotypes. This imbalance amplifies splenic monocyte release and sustains cardiac inflammation. Concurrently, excessive inflammatory mediators and insufficient TGF‐β impair fibroblast activation, delaying ...
Xingxu Zhang, Yuan Fang, Xiaoming Qin, Yiwei Zhang, Bo Kang, Li Zhong, Baoxin Liu, Jiachen Luo, Yidong Wei   +8 more
wiley   +1 more source

Assessment of Intraspecific Variability in the Forest Dormouse (<i>Dryomys nitedula</i>) and Woolly Dormouse (<i>Dryomys laniger</i>) from Türkiye and Adjacent Regions Based on Mitochondrial DNA. [PDF]

Life (Basel)
Çolak E, Markov G, Selvi E, Kankılıç T, Şeker PS, Kocheva MA, Gospodinova MK, Çolak R, Dimitrov H, Yiğit N.   +9 more
europepmc   +1 more source

Reinforcing Stromal Cell Spheroid Through Red‐Light Preconditioning for Advanced Vascularization

Advanced Science, EarlyView.
This study presents a novel approach to enhance stromal cell therapy for myocardial infarction by combining OLED‐based photobiomodulation (OPBM) preconditioning with 3D spheroid culture of hADSCs. The engineered spheroids improve angiogenesis, arterialization, and cardiac function in vivo, offering a next‐generation therapeutic strategy to overcome ...
Yu‐Jin Kim, Hyeok Kim, Dong‐Hyun Lee, Yeong Hwan Kim, Jae‐Hyun Park, Woo‐Sup Sim, Jin‐Ju Kim, Kiwon Ban, Soong Ho Um, Hyun Ji Park, Michael E. Davis, Hun‐Jun Park, Suk Ho Bhang   +12 more
wiley   +1 more source

Genetic diversity and novel haplotypes of <i>Apis mellifera jemenitica</i> on the Arabian Peninsula: insights from mtDNA markers. [PDF]

Front Genet
Alsharhi M, Al-Ghamdi A, Al-Garadi MA, Alburaki M.   +3 more
europepmc   +1 more source