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Cell lineage, embryogenesis and mouse molecular genetics

Theriogenology, 1997
Abstract Pluripotent stem cells are present in the murine embryo until at least the 64-cell stage (day 3.5 of development). These cells can be cultured in vitro and genetically modified to fulfill various specific requirements. After re-introduction into a host blastocyst, which then develops to maturity, they colonize all tissues, including the germ-
R. Moore, R. Kemler
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Genetic Lineage Tracing Analysis of Anterior Hox Expressing Cells

2014
Cell lineage studies have been widely used in developmental biology to establish which cells, and how many cells, in the early embryo will give rise to a specific structure and its derivatives. Several methods have been developed to label progenitor cells in the early embryo.
Laforest, B., Bertrand, N., Zaffran, S.
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Genetic Mosaicism in Adult Mice of Quadriparental Lineage

Science, 1965
Genetic mosaic mice can be produced by aggregating, during cleavage stages, the blastomeres of two embryos of different genotype into a single cluster, and by transferring the developing aggregates to the uterus of a surrogate mother. Substantial numbers of such composite embryos survive past birth.
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Genetic mosaics and cell lineage analysis in plants

Trends in Genetics, 1989
The use of genetic mosaics for cell lineage analysis has revealed several important features of plant development. All multicellular organs in higher plants are polyclonal in origin. Although primordial cell lineages have fairly regular fates, the fate of any given cell within these lineages cannot be accurately predicted.
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Genetic diversity of Croatian paternal lineages

2003
The purpose of this study was to examine population structure based on the polymorphisms of biallelic (M8, YAP, SRY-1532, 92R7, SRY-8299/4064, 12f2, M20, M52, M70, M89, M124, M170, M201, M173, M175) and eight microsatelitte markers (DYS19, DYS388, DYS389I, DYS389II, DYS390, DYS391, DYS392 and DYS393) in 457 Croatian Y chromosomes.
Martinović Klarić, Irena   +4 more
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Genetic Lineage Tracing of Nonmyocyte Population by Dual Recombinases

Circulation, 2018
Background: Whether the adult mammalian heart harbors cardiac stem cells for regeneration of cardiomyocytes is an important yet contentious topic in the field of cardiovascular regeneration.
Yan, Li   +20 more
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Genetic lineage tracing identifies endocardial origin of liver vasculature

Nature Genetics, 2016
The hepatic vasculature is essential for liver development, homeostasis and regeneration, yet the developmental program of hepatic vessel formation and the embryonic origin of the liver vasculature remain unknown. Here we show in mouse that endocardial cells form a primitive vascular plexus surrounding the liver bud and subsequently contribute to a ...
Hui, Zhang   +11 more
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Introduction: The Malecot Lineage in Population Genetics

2002
Abstract Gustave Malecot (1911-1998) was one of the pioneers of theoretical population genetics. He introduced some of the fundamental methods and principles of the field, yet because he wrote most of his papers in French and because some of his methods were developed long before they could be applied to data, Malecot’s work has been ...
Michel Veuille, Montgomery Slatkin
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Genetic Lineages of Mycobacterium tuberculosis Isolates in Isfahan, Iran

Current Microbiology, 2016
In this study, we aimed to identify the genetic lineages of Mycobacterium tuberculosis isolates in Isfahan via the mycobacterial interspersed repetitive-unit-variable number tandem repeat typing method based on 15 loci. Forty-nine M. tuberculosis isolates were collected between 2013 and 2015 from Tuberculosis patients in Mollahadi Sabzevari ...
Fatemeh, Riyahi Zaniani   +6 more
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From cell lineage to developmental genetics.

History and philosophy of the life sciences, 1998
One of the bases of developmental genetics resides in the alliance of clonal analysis and genetic analysis. But the study of cell lineage--cells which have their genealogical relationship--and the study of the cellular labelled progeny, have their own history. We have tried to follow it since its foundation with C.O. Whitman (1878) and E.B.
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