Results 261 to 270 of about 503,355 (348)

Notch Mediates a Genetic Switch in Neural Lineage Topology

Developmental Biology, 2011
Stefan Thor, Ryan B. MacDonald, Caroline Bivik, Magnus Baumgardt, Daniel Karlsson, Carina Ulvklo   +5 more
openaire   +2 more sources

The FGF13‐Caveolin‐1 Axis: A Key Player in the Pathogenesis of Doxorubicin‐ and D‐Galactose‐Induced Premature Cardiac Aging

Advanced Science, EarlyView.
The FGF13 level is significantly downregulated in premature aging murine hearts subject to D‐galactose and Doxorubicin. FGF13 overexpression and deficiency exacerbated and alleviated Doxorubicin/D‐galactose‐induced myocardial aging characteristics and functional impairment, respectively.
Enzhao Shen, Yuecheng Wu, Weijian Ye, Sihang Li, Junjie Zhu, Meifan Jiang, Zhicheng Hu, Gaoyong Cao, Xiaojing Yi, Fan Li, Zhouhao Tang, Xiaokun Li, Kwang Youl Lee, Litai Jin, Xu Wang, Weitao Cong   +15 more
wiley   +1 more source

Evolutionary Origin and Genetic Diversity of the Pannonian Ecotype of <i>Apis mellifera carnica</i> Colonies in Hungary Based on Mitochondrial DNA and Microsatellite Markers. [PDF]

Biology (Basel)
Balazs R, Molnar TG, Edvine Meleg E, Hidas A, Zajacz E, Racz T, Palinkas-Bodzsar N.   +6 more
europepmc   +1 more source

Functional Genetic Diversity among Mycobacterium tuberculosis Complex Clinical Isolates: Delineation of Conserved Core and Lineage-Specific Transcriptomes during Intracellular Survival

, 2010
Susanne Homolka, Stefan Niemann, David G. Russell, Kyle H. Rohde   +3 more
openalex   +2 more sources

Generation of Neural Organoids and Their Application in Disease Modeling and Regenerative Medicine

Advanced Science, EarlyView.
Neural organoids provide a versatile platform for neurological research. Advances in organoid technology have partially achieved human neural tissue complexity in terms of tissue structure, cell diversity, and neural signaling, offering insights into neural disorders and regenerative strategies. Technology advances from biomaterials, bio‐manufacturing,
Ruiqi Huang, Feng Gao, Liqun Yu, Haokun Chen, Rongrong Zhu   +4 more
wiley   +1 more source

Diverse Genetic Mechanisms Enable Pseudomonas syringae to Rapidly Overcome Effector-Triggered Immunity. [PDF]

Mol Plant Pathol
Newfeld J, Bull E, Shata E, Perc M, Tang RX, Dillon MM.   +5 more
europepmc   +1 more source

Revisiting genetic structuring in spotted gums (genus Corymbia section Maculatae) focusing on C. maculata, an early diverged, insular lineage

, 2011
Mervyn Shepherd, Michael Henson, David J. Lee   +2 more
openalex   +1 more source

A Super‐Enhancer‐Driven Transcriptional Regulatory Circuit Underlying Abiraterone Resistance in Castration‐Resistant Prostate Cancer

Advanced Science, EarlyView.
This study identifies a super‐enhancer‐driven transcriptional regulatory circuit comprising BCL6, SMAD3, and NFIB that cooperate to drive cholesterol synthesis via SREBF2/HMGCR/FDFT1 activation and regulate CDK2/CCND3 for cell cycle control. Targeting this circuit with BI‐3802 or downstream inhibitors (Fatostatin/Lovastatin) overcomes abiraterone ...
Liling Jiang, Jiamin Wang, Guanjie Peng, Haichuan Zhang, Jinxin Fang, Yingyin Gao, Enzhe Lou, Yangzhou Liu, Wa Ding, Bingyuan Liu, Qiong Mao, Lizhen Jiang, Aochu Liu, Xinyue Li, Shiwen Hu, Qiaomin Ma, Yueyuan Zheng, Zhigang Zhao, Xianping Shi   +18 more
wiley   +1 more source

Understanding the epidemiology and pathogenesis of Mycobacterium tuberculosis with non-redundant pangenome of epidemic strains in China. [PDF]

PLoS One
Zhou Y, Anthony R, Wang S, Xia H, Ou X, Zhao B, Song Y, Zheng Y, He P, Liu D, Zhao Y, van Soolingen D.   +11 more
europepmc   +1 more source

Comparison between Immunohistochemistry and Genetic Clonality Analysis for Cellular Lineage Determination in Feline Lymphomas

, 2011
Hirofumi Sato, Yasuhito Fujino, Kazuyuki Uchida, Koichi Ohno, Hiroyuki Nakayama, Hajime Tsujimoto   +5 more
openalex   +2 more sources