Results 281 to 290 of about 533,076 (344)

Exploration of Novel Biomarkers Through a Precision Medicine Approach Using Multi‐Omics and Brain Organoids in Patients With Atypical Depression and Psychotic Symptoms

Advanced Science, EarlyView.
This study examines major depressive disorder with atypical features and psychotic symptoms through a multi‐omics precision medicine approach. By integrating clinical assessments, WBC scRNA‐seq, plasma proteomics, and brain organoid models, it uncovers immune dysregulation, synaptic protein alterations, and stress‐sensitive neuronal changes.
Insook Ahn, Soyeon Chang, Jiyoung Lee, Seok‐Ho Choi, Jinju Han, Yangsik Kim   +5 more
wiley   +1 more source

Letter to the Editor: The Lineage and Sublineage Investigation of Human Papillomavirus Type 16 in Tehran, Iran, During 2022-2023. [PDF]

Health Sci Rep
Shakir S, Ali SH, Iqbal J.
europepmc   +1 more source

Neutrophil Extracellular Trap Reprograms Cancer Metabolism to Form a Metastatic Niche Promoting Non‐Small Cell Lung Cancer Brain Metastasis

Advanced Science, EarlyView.
This study mainly combines spatial/single‐cell transcriptomics and metabolomics to reveal LOX+ Malig‐5 as NSCLC brain metastasis‐initiating cells, forming a niche with NET‐releasing neutrophils via the NET‐KRT10 axis. The metastatic niche is involved with metabolic reprogramming, with palmitic acid serving as a key metabolite.
Bo Chen, Karrie M. Kiang, Fangkun Liu, Chuntao Li, Xizhe Li, Chen Weiwei, Xin Fu, Gelei Xiao, Jingyi Sun, Erhan Da, Junbo Liao, Hongshu Zhou, Li Meng, Li Zhou, Tao Song, Longbo Zhang, Gilberto Ka‐Kit Leung, Liyang Zhang   +17 more
wiley   +1 more source

Genomic Characterization of Predominant Delta Variant (B.1.617.2 and AY.120 Sub-Lineages) SARS-CoV-2 Detected from AFI Patients in Ethiopia During 2021-2022. [PDF]

Genes (Basel)
Chekol MT, Teklu DS, Tayachew A, Shura W, Agune A, Hailemariam A, Alemu A, Wossen M, Hassen A, Gonta M, Tesfay N, Kasa T, Kebede N.   +12 more
europepmc   +1 more source

Mesenchymal Stem Cell‐Derived Extracellular Vesicles Modulate the Course of Peritoneal Inflammation Through Metabolic and Epigenetic Regulation

Advanced Science, EarlyView.
MSC‐EVs alleviate peritoneal inflammation and fibrogenesis by disrupting the H3K18la‐CCL2 axis and crosstalk between mesothelial cells and Ly6c2⁺ macrophages. Model cartoons are constructed using the Biorender website (https://www.biorender.com/), and a usage license is obtained. Abstract Peritoneal dialysis (PD), as a renal replacement therapy, relies
Qiang Huang, Yuxiang Sun, Pengpeng Kuang, Juan Sun, Dandan Guo, Long Peng, Hu Zhou, Qinrong Song, Zhihao Huo, Canming Li, Janusz Witowski, Zhaoyong Hu, Hui Peng   +12 more
wiley   +1 more source

Genomic characterization and evolution analysis of peste des petits ruminants virus in China from 2007 to 2024. [PDF]

Front Microbiol
Bao J, Jiang R, Wang S, Wang Q, Xu J, Zhao Y, Liu Y, Li L, Wang X, Wang Z.   +9 more
europepmc   +1 more source

Dynamic Fibrous Hydrogels for Stem Cell Homing and In Situ Bone Regeneration

Advanced Science, EarlyView.
A dynamic fibrous hydrogel (DFH) is developed by covalent crosslinking of gelatin with tea‐derived trichomes, which integrates the structural and compositional fidelity of native extracellular matrix with photothermal and oxidative responsiveness, introducing a novel “stem cell recruits stem cell” strategy that orchestrates co‐homing of endogenous and ...
Jianmei Chen, Meiling Su, Xinyu Wu, Hongyu Wu, Haotian Wu, Pinghu Zhang, Xueying An, Zongguang Liu   +7 more
wiley   +1 more source

Genetic Diversity and Temporal Shifts of Porcine Reproductive and Respiratory Syndrome Virus Type 2 (PRRSV-2) Strains in Japan (2020-2023): Evidence of Modified Live Vaccine Influence on Cluster Distribution. [PDF]

Epidemiologia (Basel)
Yonezawa Y, Taira O, Kato A, Takai R, Nukui R, Tsutsumi N, Matsuyama R, Makita K.   +7 more
europepmc   +1 more source

Polyphyletic domestication and inter-lineage hybridization magnified genetic diversity of cultivated melon, <i>Cucumis melo</i> L.

Katsunori Tanaka, Gentaro Shigita, Tran Phuong Dung, Phan Thị Phương Nhi, Mami Takahashi, Yuki Monden, Hidetaka Nishida, Ryuji Ishikawa, Kenji Kato   +8 more
openalex   +2 more sources

Transposable elements: a key piece in the genomic evolution and adaptation of Myrtaceae species. [PDF]

Mob DNA
Waschburger EL, Filgueiras JPC, Antoniolli HDRM, Deprá M, Guyot R, Turchetto-Zolet AC.   +5 more
europepmc   +1 more source