Results 121 to 130 of about 5,206,546 (317)
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
It is well known that beamstrahlung and bremsstrahlung take place over a finite formation zone distance. If something disturbs the electron during this time, the emission can be suppressed.
Chen, Pisin (Stanford Linear Accelerator Center, Menlo Park, CA (United States)) +1 more
core
GM1 and GM2 gangliosides: recent developments
GM1 and GM2 gangliosides are important components of the cell membrane and play an integral role in cell signaling and metabolism. In this conceptual overview, we discuss recent developments in our understanding of the basic biological functions of GM1 ...
Bisel Blaine +2 more
doaj +1 more source
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
Using Maple or Mathmatica, learner should be able to examine linear transformations, particularly those from R2 to ...
Smith, David
core
Diversity and complexity in neural organoids
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
Multivariate Linear Hypothesis with Linear Restrictions
SUMMARY In this paper we consider a normal multivariate linear regression model and give a criterion for the simultaneous testing of a set of linear estimable parametric functions. We also derive the distribution of the criterion and obtain some allied results.
openaire +2 more sources
Aims and Scope Manuscripts submitted to Numerical Linear Algebra with Applications should include large-scale broad-interest applications in which challenging computational results are integral to the approach investigated and analysed.
SIMONCINI, VALERIA
core
Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source
This course introduces the student to the study of linear algebra. Practically every modern technology relies on linear algebra to simplify the computations required for internet searches, 3-D animation, coordination of safety systems, financial trading,
The Saylor Foundation
core

