Results 71 to 80 of about 199,141 (285)

Ocular Complications of Radiotherapy for Head and Neck Tumours

Delhi Journal of Ophthalmology, 2019
Aim: To study the various ocular complications associated with radiotherapy and correlate them with duration & dose of radiation. Design: Hospital based prospective study Methods: The present study comprises of 100 patients of head and neck tumors who ...
Sarita Maharia, Kalpna Jain, H. S. Kumar
doaj   +1 more source

Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer

Molecular Oncology, EarlyView.
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni, Antonella Palmese, Stefano Scalera, Laura Cipriani, Davide Mascolo, Patrizia Vici, Teresa Arcuri, Lorena Filomeno, Eriseld Krasniqi, Giovanni Blandino, Giulia Bon, Marcello Maugeri‐Saccà   +11 more
wiley   +1 more source

Ion-hose instability in a long-pulse linear induction accelerator

Physical Review Special Topics. Accelerators and Beams, 2003
The ion-hose instability is a transverse electrostatic instability which occurs on electron beams in the presence of a low-density ion channel. It is a phenomenon quite similar to the interaction between electron clouds and proton or positron beams in ...
Thomas C. Genoni, Thomas P. Hughes
doaj   +1 more source

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

Molecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova, Michele Montrone, Uday Rangaswamy, Francesco Diversi, Irene Schiavo, Denise Ferrarini, Roberta Di Florio, Irene Longo, Michele Coscia, Nicola Zamboni, Giorgia Demontis, Lisa Veghini, Vincenzo Corbo, Remo Sanges, Paul Heppenstall   +14 more
wiley   +1 more source

Vibration isolation measures due to the high sensitive linear accelerator at the Paul Scherrer Institute

MATEC Web of Conferences, 2015
The new 735m long linear accelerator “SwissFEL” at the Paul Scherrer Institute (PSI) in Würenlingen is extremely sensitive against vibrations coming from surrounding equipment (pumps, ventilators, transformers, etc.).
Trombik Peter, Fleischer Pascal, Vassiliou Michalis F.   +2 more
doaj   +1 more source

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

Molecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu, Xixi Lin, Emil Mladenov, Veronika Mladenova, Jürgen Thomale, Ali Sak, Yao Wang, Yunxuan Deng, Eleni Gkika, Martin Stuschke, George Iliakis   +10 more
wiley   +1 more source

Determining X-Ray Effective Energy in Linear Accelerator (LINAC) Radiotherapy Instrument

Jurnal Ilmiah Pendidikan Fisika Al-Biruni, 2018
This research in determining x-ray effective energy in linear accelerator (Linac) radiotherapy device was done using copper plates at different thicknesses by determining the Half Value Layer (HVL) for each energy. The purpose of this research is to know
Fauziah Fauziah, Bualkar Abdullah
doaj   +1 more source

Positrons sources and related activities for Future Linear Collider at LAL Orsay Laboratory

, 2011
In the context of the positrons sources studies for the Future Linear Collider, the Accelerator Department at LAL Orsay is involved since several years in different activities both experiments and simulations.Comment ...
Dadoun, Olivier
core   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

Molecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Estimation of Primary Electron Beam Parameters of Individual Linear Accelerator Using Monte Carlo Method

Zhongguo yiliao qixie zazhi
ObjectiveTo estimate the primary electron beam parameters (PEB), including energy, radial intensity distribution and average angular divergence, of the individual linear accelerator using the Monte Carlo method. MethodsA model of the treatment head and a
Yisong HE, Hang YU, Yuchuan FU, Jinyou HU, Lian ZOU   +4 more
doaj   +1 more source