Results 51 to 60 of about 3,215,324 (277)
Organoids in pediatric cancer research
FEBS Letters, EarlyView.Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley +1 more source
Combined approach to solve linear complementarity problem
Journal of Numerical Analysis and Approximation Theory, 2016 In this paper, we present a new approach in order to solve the linear complementary problem noted (LCP). We have combined the ideas of Lemke's method and its variants taking advantage of the benefits of each approach in order to improve the convergence ...
Kebbiche Zakia, Roumili Hayet
doaj +2 more sources
Improved Full-Newton-Step Infeasible Interior-Point Method for Linear Complementarity Problems
Croatian Operational Research Review, 2016 We present an Infeasible Interior-Point Method for monotone Linear Complementarity Problem (LCP) which is an improved version of the algorithm given in [13]. In the earlier version, each iteration consisted of one feasibility step and few centering steps.
Goran Lešaja, Mustafa Ozen
doaj +1 more source
Diversity and complexity in neural organoids
FEBS Letters, EarlyView.Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
LINEAR COMPLEMENTARITY AND ORIENTED MATROIDS
Journal of the Operations Research Society of Japan, 1992 Summary: A combinatorial abstraction of the linear complementarity theory in the setting of oriented matroids was first considered by \textit{M. J. Todd} [SIAM J. Algebraic Discrete Methods 5, 467-485 (1984; Zbl 0556.05016)]. We take a fresh look at this abstraction, and attempt to give a simple treatment of the combinatorial theory of linear ...
Fukuda, Komei, Terlaky, Tamas
openaire +2 more sources
FEBS Letters, EarlyView.Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley +1 more source
FEBS Letters, EarlyView.Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley +1 more source
Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
On the convergence of SOR- and JOR-type methods for convex linear complementarity problems
, 1991 We consider SOR- and JOR-type iterative methods for solving linear complementarity problems. If the solution set is not discrete, weak-convergence proofs are usually obtained for these methods; i.e., every accumulation point of the generated sequence is ...
Alfredo N. Iusem +3 more
core +2 more sources