Results 71 to 80 of about 3,215,324 (277)
FEBS Letters, EarlyView.This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee +2 more
wiley +1 more source
A Preconditioned Multisplitting and Schwarz Method for Linear Complementarity Problem
Journal of Applied Mathematics, 2014 The preconditioner presented by Hadjidimos et al. (2003) can improve on the convergence rate of the classical iterative methods to solve linear systems.
Cuiyu Liu, Chen-liang Li
doaj +1 more source
Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding
FEBS Letters, EarlyView.In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança +2 more
wiley +1 more source
Absolute Value Equation Solution via Dual Complementarity [PDF]
, 2011 By utilizing a dual complementarity condition, we propose an iterative method for solving the NPhard absolute value equation (AVE): Ax?|x| = b, where A is an n n square matrix.
Mangasarian, Olvi
core
Translophagy—A potential link between autophagy impairment and translational errors
FEBS Letters, EarlyView.Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk +11 more
wiley +1 more source
Prospecting the protein design landscape
FEBS Letters, EarlyView.This review outlines the current state of various protein design approaches. We discuss the current possibilities enabled by recently released tools, highlight future avenues to pursue in protein design, and underscore the crucial role of key databases and resources for successful protein design workflows.
Jakob R. Riccabona +4 more
wiley +1 more source
On degeneracy in linear complementarity problems
Discrete Applied Mathematics, 1985 This paper presents a method for handling degeneracy in linear complementarity problems. The method is based on the sequential (variable-dimension) version of Lemke's algorithm. Curiously, the paper makes no mention of other publications pertaining to degeneracy handling in Lemke's method or any other.
openaire +3 more sources
RNA‐related functions of BRCA2 in transcription, replication, and genome stability
FEBS Letters, EarlyView.Beyond its role in homologous recombination, BRCA2 regulates R‐loop homeostasis, DNA–RNA hybrid resolution, RNA polymerase II dynamics, and transcriptional activation. Disruption of any of these functions can contribute to genome instability, inflammatory signaling, and tumorigenesis. BRCA2 is a central tumor suppressor protein best known for its roles
Lucia Alvaro‐Aranda +2 more
wiley +1 more source
A new Approach for the Modulus-Based Matrix Splitting Algorithms
IEEE Access, 2019 We investigate the modulus-based matrix splitting iteration algorithms for solving the linear complementarity problems (LCPs) and propose a new model to solve it.
Wenpeng Wang +3 more
doaj +1 more source
FEBS Letters, EarlyView.Heterodimeric amino acid transporters consist of SLC7 and SLC3 family proteins arranged in a conserved structural organization. They regulate nutrient transport across cell membranes, supporting essential cellular functions. These transporters also contribute to xenobiotic/drug uptake and distribution.
Mariafrancesca Scalise +5 more
wiley +1 more source