Peptide‐based ligand antagonists block a Vibrio cholerae adhesin
The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang +9 more
wiley +1 more source
Optimal linear power flow for droop controlled islanded microgrid
The time of optimal planning and operation of islanded microgrid (IMG) can be minimized by modeling it as non-iterative mixed integer linear problem (MILP).
Ankit Uniyal +2 more
doaj +1 more source
Analytical Solution to the MHD Flow of Micropolar Fluid Over a Linear Stretching Sheet
The flow due to a linear stretching sheet in a fluid with suspended particles, modeled as a micropolar fluid, is considered. All reported works on the problem use numerical methods of solution or a regular perturbation technique.
P.G. Siddheshwar, U.S. Mahabaleshwar
doaj +1 more source
Flow of low energy couplings in the Wilson renormalization group
A new form of the Wilson renormalization group equation is derived, in which the flow equations are, up to linear terms, proportional to a gradient flow.
Myers, Robert C., Periwal, Vipul
core +1 more source
Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer
Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani +4 more
wiley +1 more source
Using mathematical formalism borrowed from dynamical systems theory, a complete analytical investigation of the critical behaviour of the stationary flow configuration for the low angular momentum axisymmetric black hole accretion provides valuable ...
Abraham +99 more
core +1 more source
Function‐driven design of a surrogate interleukin‐2 receptor ligand
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang +9 more
wiley +1 more source
Functional Microbial Communities in Hybrid Linear Flow Channel Reactors for Desulfurization of Tannery Effluent. [PDF]
Horn EJ +3 more
europepmc +1 more source
Mechanisms of parasite‐mediated disruption of brain vessels
Parasites can affect the blood vessels of the brain, often causing serious neurological problems. This review explains how different parasites interact with and disrupt these vessels, what this means for brain health, and why these processes matter. Understanding these mechanisms may help us develop better ways to prevent or treat brain infections in ...
Leonor Loira +3 more
wiley +1 more source
Effect of temperature change on the performance of the hybrid linear flow channel reactor and its implications on sulphate-reducing and sulphide-oxidising microbial community dynamics. [PDF]
Marais TS +3 more
europepmc +1 more source

