Results 121 to 130 of about 3,117,054 (342)

Flow regime transition maps and pressure loss prediction of gas, oil and water three-phase flow in the vertical riser downstream 90° bend using data driven approach

open access: yesDigital Chemical Engineering
The simultaneous flow of gas, oil & water is frequently encountered in pipelines during upstream petroleum operations. The multiphase flow results in different types of flow patterns based on the flow rates of fluids, physical properties and geometry
Muhammad Waqas Yaqub   +1 more
doaj   +1 more source

Design factors for “linear” ball valve: theoretical and experimental studies [PDF]

open access: yesSongklanakarin Journal of Science and Technology (SJST), 2005
Generic non-linear flow characteristics of the conventional ball valve limit the applications of flow modulation in fluid processes. This work presents the flow characteristics of fluid flowing through the conventional and modified ball valves for ...
Thananchai Leephakpreeda
doaj  

Linear Post-Linear Flow Production Analysis [PDF]

open access: yesProceedings of the 5th Unconventional Resources Technology Conference, 2017
Trent Bone   +2 more
openaire   +1 more source

A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression

open access: yesMolecular Oncology, EarlyView.
Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak   +8 more
wiley   +1 more source

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

open access: yesMolecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker   +16 more
wiley   +1 more source

Predictors of response and rational combinations for the novel MCL‐1 inhibitor MIK665 in acute myeloid leukemia

open access: yesMolecular Oncology, EarlyView.
This study characterizes the responses of primary acute myeloid leukemia (AML) patient samples to the MCL‐1 inhibitor MIK665. The results revealed that monocytic differentiation is associated with MIK665 sensitivity. Conversely, elevated ABCB1 expression is a potential biomarker of resistance to the treatment, which can be overcome by the combination ...
Joseph Saad   +17 more
wiley   +1 more source

Influence of the wall roughness on a linear shear flow [PDF]

open access: yesFME Transactions, 2018
In this paper, we will be interested in the viscous flow fluid over a rough wall which has a periodic roughness and small amplitude. The Reynolds number for the flow over a rough wall is low and the creeping flow equations apply.
Assoudi Redouane   +2 more
doaj  

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