Results 91 to 100 of about 89,989 (306)
COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos +6 more
wiley +1 more source
Linear Hyperbolic Functional-Differential Equations with Essentially Bounded Right-Hand Side
Theorems on the unique solvability and nonnegativity of solutions to the characteristic initial value problem u1,1(t,x)=l0(u)(t,x)+l1(u1,0)(t,x)+l2(u0,1)(t,x)+q(t,x), u(t,c)=α(t) for t∈[a,b], u(a,x)=β(x) for x∈[c,d] given on ...
Alexander Domoshnitsky +3 more
doaj +1 more source
Multivariable Calculus, Linear Algebra, and Differential Equations
Multivariable Calculus, Linear Algebra, and Differential Equations, Second Edition contains a comprehensive coverage of the study of advanced calculus, linear algebra, and differential equations for sophomore college students.The text includes a large ...
Grossman, Stanley I.
core
On the asymptotic behaviour of deterministic and stochastic volterra integro-differential equations [PDF]
This thesis examines a question of stability in stochastic and deterministic systems with memory, and involves studying the asymptotic properties of Volterra integro-differential equations.
Devin, Siobhan
core
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen +11 more
wiley +1 more source
Inspired by the construction of a new Liapunov functional for linear Volterra integrodifferential equations, we prove some general stability theorems for functional differential equations with infinite delay and weaken the usual requirement for positive ...
Bo Zhang
doaj +1 more source
The exact conditions sufficient for the unique solvability of the initial value problem for a system of linear fractional functional differential equations determined by isotone operators are established.
Michal Fečkan, Natalia Dilna
core +1 more source
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source
On Nonseparated Three-Point Boundary Value Problems for Linear Functional Differential Equations
For a system of linear functional differential equations, we consider a three-point problem with nonseparated boundary conditions determined by singular matrices.
A. Rontó, M. Rontó
doaj +1 more source
In this paper we investigate the transversality of homoclinic orbits in partial functional differential equations. We first discuss the exponential dichotomies for linear operator equations.
Ruan, Shigui, Zhang, Weinian
core +1 more source

