Results 101 to 110 of about 89,989 (306)
Molecular Oncology, EarlyView.EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain +10 more
wiley +1 more source
Instability of Non-Linear Functional Differential Equations of Fifth Order
Journal of Mathematical and Fundamental Sciences, 2014 In this paper, we study the instability properties of solutions of a kind of functional differential equations of the fifth order with constant delay. Using the Lyapunov-Krasovskii functional approach, we obtain certain sufficient conditions to guarantee
Cemil Tunc
doaj
Integrating Bernstein and Improved Block-Pulse Functions for Solving Linear Fredholm Integro-Differential Equations [PDF]
Egyptian Journal of Pure and Applied ScienceMathematical modeling of real-life problems usually results in some form of functional equations, e.g. algebraic equations, differential equations, integral equations and others.
Mohamed Ramadan, Heba Osheba
doaj +1 more source
, 2023 The equation G(x,x)=y˜, where G:X×X→Y, and X,Y are vector metric spaces (meaning that the values of a distance between the points in these spaces belong to some cones E+,M+ of a Banach space E and a linear space M, respectively), is ...
Evgeny Zhukovskiy, Elena Panasenko
core +1 more source
Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer
Molecular Oncology, EarlyView.Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley +1 more source
Global extrapolation procedures for linear partial differential equations
, 1987 Global extrapolation procedures, in space and time are considered for the numerical Solution of linear partial differential equations. Global extrapolation procedures in time only are reviewed.
Twizell, E H
core
Prabhakar-type linear differential equations with variable coefficients
, 2022 Linear differential equations with variable coefficients and Prabhakar-type operators featuring Mittag-Leffler kernels are solved. In each case, the unique solution is constructed explicitly as a convergent infinite series involving compositions of ...
Fernandez, Arran +2 more
core
Molecular Oncology, EarlyView.Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura +19 more
wiley +1 more source
New Oscillation Criteria for Second-Order Forced Quasilinear Functional Differential Equations
Abstract and Applied Analysis, 2013 We establish some new interval oscillation criteria for a general class of second-order forced quasilinear functional differential equations with ϕ-Laplacian operator and mixed nonlinearities.
Mervan Pašić
doaj +1 more source
, 2020 This article presents a reformulation of the Theory of Functional Connections: a general methodology for functional interpolation that can embed a set of user-specified linear constraints. The reformulation presented in this paper exploits the underlying
Daniele Mortari +2 more
core +1 more source