Results 71 to 80 of about 428,756 (295)

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

open access: yesFEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel   +13 more
wiley   +1 more source

Uniform exponential stability of linear periodic systems in a Banach space

open access: yesElectronic Journal of Differential Equations, 2001
This article is devoted to the study of linear periodic dynamical systems, possessing the property of uniform exponential stability. It is proved that if the Cauchy operator of these systems possesses a certain compactness property, then the asymptotic ...
David N. Cheban
doaj  

Linear Quadratic Stochastic Optimal Control Problems with Operator Coefficients: Open-Loop Solutions

open access: yes, 2019
An optimal control problem is considered for linear stochastic differential equations with quadratic cost functional. The coefficients of the state equation and the weights in the cost functional are bounded operators on the spaces of square integrable ...
Wei, Qingmeng   +2 more
core   +1 more source

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Differential Inequalities for One Component of Solution Vector for Systems of Linear Functional Differential Equations

open access: yesAdvances in Difference Equations, 2010
The method to compare only one component of the solution vector of linear functional differential systems, which does not require heavy sign restrictions on their coefficients, is proposed in this paper.
Alexander Domoshnitsky
doaj   +2 more sources

On a boundary value problem for scalar linear functional differential equations

open access: yesAbstract and Applied Analysis, 2004
Theorems on the Fredholm alternative and well-posedness of the linear boundary value problem u′(t)=ℓ(u)(t)+q(t), h(u)=c, where ℓ:C([a,b];ℝ)→L([a,b];ℝ) and h:C([a,b];ℝ)→ℝ are linear bounded operators, q∈L([a,b];ℝ), and c∈ℝ, are established even in the ...
R. Hakl   +2 more
doaj   +1 more source

Asymptotic behavior of perturbed autonomous linear functional differential equations [PDF]

open access: yesProceedings of the American Mathematical Society, 1975
It is shown that certain autonomous linear functional differential equations and their perturbations satisfy a generalized type of asymptotic equivalence. An example is given.
openaire   +2 more sources

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

open access: yesMolecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice   +16 more
wiley   +1 more source

Uniform exponential stability of linear almost periodic systems in Banach spaces

open access: yesElectronic Journal of Differential Equations, 2000
This article is devoted to the study linear non-autonomous dynamical systems possessing the property of uniform exponential stability. We prove that if the Cauchy operator of these systems possesses a certain compactness property, then the uniform ...
David N. Cheban
doaj  

Functional representation of the Ablowitz-Ladik hierarchy

open access: yes, 1997
The Ablowitz-Ladik hierarchy (ALH) is considered in the framework of the inverse scattering approach. After establishing the structure of solutions of the auxiliary linear problems, the ALH, which has been originally introduced as an infinite system of ...
Ablowitz M J   +14 more
core   +1 more source

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