Results 71 to 80 of about 560,929 (291)
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
Interpolation of compact non-linear operators
Let and be two Banach couples and let be a continuous map such that is a Lipschitz compact operator and is a Lipschitz operator. We prove that if is also compact or is continuously embedded in or is continuously embedded in , then is also a ...
Bento AJG
doaj
Interpolation of discount factors [PDF]
This paper deals with the problem of interpolation of discount factors between time buckets. The problem occurs when price and interest rate data of a market segment are assigned to discrete time buckets.
Cremers, Heinz, Schwarz, Willi
core
Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway
Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed +10 more
wiley +1 more source
Towards a More General Type of Univariate Constrained Interpolation With Fractal Splines
Recently, in [Electronic Transaction on Numerical Analysis, 41 (2014), pp. 420-442] authors introduced a new class of rational cubic fractal interpolation functions with linear denominators via fractal perturbation of traditional nonrecursive rational ...
Chand, A. K. B. +2 more
core +1 more source
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra +10 more
wiley +1 more source
We developed and validated a DNA methylation–based biomarker panel to distinguish pleural mesothelioma from other pleural conditions. Using the IMPRESS technology, we translated this panel into a clinically applicable assay. The resulting two classifier models demonstrated excellent performance, achieving high AUC values and strong diagnostic accuracy.
Janah Vandenhoeck +12 more
wiley +1 more source
Imputation and Price Indexes: Theory and Evidence from the International Price Program [PDF]
The goal of this paper is to theoretically and empirically demonstrate the consequences of different imputation methods, using recent data from the International Price Program. We suppose that prices are missing due to random or erratic reporting.
Erwin Diewert, Robert Feenstra
core
Dualities in fractional statistics
We first reobtain in a simpler way the Haldane fractional statistics at thermal equilibrium using an interpolation argument. We then show that the mean occupation number for fractional statistics is invariant to a group of duality transformations, a ...
Buyukkihc F., Einstein A., M. I. Beciu
core +1 more source
Potential therapeutic targeting of BKCa channels in glioblastoma treatment
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak +4 more
wiley +1 more source

