Results 51 to 60 of about 113,300 (260)

Linear Interpolation

, 2021
This series of articles will explore one of the most used Mathematical tools in Game Development: linear interpolation! This first article will focus on its Mathematical definition and implementation.
Zucconi, Alan
core  

Reconstructing enzyme evolution by protein engineering

FEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler, Markus R. Busch, Reinhard Sterner   +2 more
wiley   +1 more source

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

Molecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce, Simone Bini, Marialuisa Sponziello, Giorgio Grani, Giulia Fiscon, Paola Paci, Lorenzo Farina, Rosa Falcone, Valentina Maggisano, Sebastiano Filetti, Cosimo Durante, Antonella Verrienti   +11 more
wiley   +1 more source

Quantifying steric hindrance and topological obstruction to protein structure superposition

Algorithms for Molecular Biology, 2021
Background In computational structural biology, structure comparison is fundamental for our understanding of proteins. Structure comparison is, e.g., algorithmically the starting point for computational studies of structural evolution and it guides our ...
Peter Røgen
doaj   +1 more source

Shifted Linear Interpolation Filter

, 2010
Linear interpolation has been adapted in many signal and image processing applications due to its simple implementa-tion and low computational cost. In standard linear interpolation the kernel is the second order B-spline β2(t). In this work we show that
Hannu Olkkonen, Olkkonen, Juuso T., Juuso T. Olkkonen, Olkkonen, H.   +3 more
core   +1 more source

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

Molecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge, Morten Tulstrup, Gabriele Todisco, Pedro Moura, Christophe Côme, Jakob Werner Hansen, Jakob Schmidt Jespersen, Balthasar Schlotmann, Maria Creignou, Mette Dahl, Claudia Schöllkopf, Klas Raaschou‐Jensen, Krister Wennerberg, Bo Porse, Joachim Weischenfeldt, Eva Hellström‐Lindberg, Lasse Sommer Kristensen, Kirsten Grønbæk   +17 more
wiley   +1 more source

Interpolation of compact non-linear operators

Journal of Inequalities and Applications, 2000
Let and be two Banach couples and let be a continuous map such that is a Lipschitz compact operator and is a Lipschitz operator. We prove that if is also compact or is continuously embedded in or is continuously embedded in , then is also a ...
Bento AJG
doaj  

Spatial interpolation using conservative fuzzy reasoning

, 2001
Spatial interpolation is an important feature of a Geographic Information System, which is the procedure used to estimate values at unknown locations within the area covered by existing observations.
Wong, K.W., Wong, P.M., Gedeon, T.
core  

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

Molecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos, Gilar Gorji‐bahri, Lejla Gradjan, Julia Zajac, Kacper Gil, Yvonne Thokozile Nduku, Anna M. Blom   +6 more
wiley   +1 more source

A Triangular Prism Spatial Interpolation Method for Mapping Geological Property Fields

ISPRS International Journal of Geo-Information, 2017
: The spatial interpolation of property fields in 3D, such as the temperature, salinity, and organic content of ocean water, is an active area of research in the applied geosciences.
Yang Cui, Qingquan Li, Qingyuan Li, Jiasong Zhu, Chisheng Wang, Kai Ding, Dan Wang, Bisheng Yang   +7 more
doaj   +1 more source