Results 41 to 50 of about 382,293 (264)

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

open access: yesFEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes   +3 more
wiley   +1 more source

Winding Function Theory Based Thrust Calculation on Nested-loop Secondary Linear Machine Adapted to Linear Metro

open access: yesCES Transactions on Electrical Machines and Systems, 2023
With advantages of strong drive capability, nested-loop secondary linear machine (NLS-LM) has great potentiality in linear metro. For its secondary structure with multiple loops, it is difficult to calculate the electromagnetic thrust of NLS-LM ...
Yaping Zhang   +6 more
doaj   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

On NP-Completeness for Linear Machines

open access: yesJournal of Complexity, 1997
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
openaire   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Time efficient variants of Twin Extreme Learning Machine

open access: yesIntelligent Systems with Applications, 2023
Twin Extreme Learning Machine models can obtain better generalization ability than the standard Extreme Learning Machine model. But, they require to solve a pair of quadratic programming problems for this.
Pritam Anand   +2 more
doaj   +1 more source

The human gut microbiome across the life course

open access: yesFEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero   +4 more
wiley   +1 more source

Study of the influence of technological processes on the breaking of any fibers

open access: yesАлматы технологиялық университетінің хабаршысы, 2021
In this work, research has been carried out on changes in the linear density of bast fibers during processing on a hammer, clog and carding machine. Physical and mechanical properties of fibers before and after processing are determined. According to the
A. A. Dulat, M. B. Otynshiyev
doaj   +1 more source

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

open access: yesFEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace   +6 more
wiley   +1 more source

A tubular hybrid Halbach/axially-magnetized permanent-magnet linear machine

open access: yesAIP Advances, 2017
A single-phase tubular permanent-magnet linear machine (PMLM) with hybrid Halbach/axially-magnetized PM arrays is proposed for free-piston Stirling power generation system. Machine topology and operating principle are elaborately illustrated.
Yi Sui   +4 more
doaj   +1 more source

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