Results 51 to 60 of about 447,541 (315)
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
FEBS Letters, EarlyView.This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
Investigation and Analysis of Force Production Mechanism for Partitioned Stator Flux Reversal Permanent Magnet Linear Machine [PDF]
Engineering and Technology Journal, 2018 In this paper, the force production mechanism in partitioned stator flux reversal permanent magnet (PS-FRPM) linear machine will be investigated. Since the PS-FRPM linear machine has both armature windings and the permanent magnet (PM) in one machine ...
Ahlam Shuraiji, Zi Zhu
doaj +1 more source
Synchronized product of linear bounded machines [PDF]
, 1999 This paper introduces a class of graphs associated to linear bounded machines. It is shown that this class is closed, up to observational equivalence, under synchronized product. The first-order theory of these graphs is investegated and shown to be undecidable. The latter result extends to any logic in which the existence of sinks may be stated.
Knapik, Teodor, Payet, Etienne
openaire +2 more sources
FEBS Letters, EarlyView.This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva +5 more
wiley +1 more source
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
High Precision Control of Flux Switching Linear Rotary Machine for Reelwinder [PDF]
, 2021 Since there is still large amplitude of the detent force of a flux switching linear rotary machine, the response time is long using space vector pulse width modulation control method when it works in linear motion at low speed.
Kaikai Guo, Youguang Guo, Guo, K, Guo, Y
core +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Time efficient variants of Twin Extreme Learning Machine
Intelligent Systems with Applications, 2023 Twin Extreme Learning Machine models can obtain better generalization ability than the standard Extreme Learning Machine model. But, they require to solve a pair of quadratic programming problems for this.
Pritam Anand +2 more
doaj +1 more source
On NP-Completeness for Linear Machines
Journal of Complexity, 1997 zbMATH Open Web Interface contents unavailable due to conflicting licenses.
openaire +1 more source
pH‐mediated activation of the lysosomal arginine sensor SLC38A9
FEBS Letters, EarlyView.Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley +1 more source