Results 91 to 100 of about 656,028 (273)
, 2012 We show that deterministic finite automata equipped with $k$ two-way heads are equivalent to deterministic machines with a single two-way input head and $k-1$ linearly bounded counters if the accepted language is strictly bounded, i.e., a subset of $a_1^*
B. Monien +9 more
core +1 more source
Molecular Oncology, EarlyView.Liquid biopsy enables minimally invasive, real‐time molecular profiling through analysis of circulating biomarkers in biological fluids. This Perspective highlights the importance of training pathologists through integrative educational programs, such as the European Masters in Molecular Pathology, to ensure effective and equitable implementation of ...
Marius Ilié +13 more
wiley +1 more source
Design and Analysis of Linear Fault-Tolerant Permanent-Magnet Vernier Machines
The Scientific World Journal, 2014 This paper proposes a new linear fault-tolerant permanent-magnet (PM) vernier (LFTPMV) machine, which can offer high thrust by using the magnetic gear effect. Both PMs and windings of the proposed machine are on short mover, while the long stator is only
Liang Xu +4 more
doaj +1 more source
Linear probabilistic sequential machines
Information and Control, 1969 Based on the notion of a stochastic matrix operator, the class of linear probabilistic sequential machines is defined and characterized. Necessary and sufficient conditions are formulated for a given probabilistic sequential machine to be linear. An algorithm for testing the linearity of a probabilistic sequential machine is presented as well.
openaire +1 more source
Next‐generation proteomics improves lung cancer risk prediction
Molecular Oncology, EarlyView.This is one of very few studies that used prediagnostic blood samples from participants of two large population‐based cohorts. We identified, evaluated, and validated an innovative protein marker model that outperformed an established risk prediction model and criteria employed by low‐dose computed tomography in lung cancer screening trials.
Megha Bhardwaj +4 more
wiley +1 more source
Molecular Oncology, EarlyView.The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg +43 more
wiley +1 more source
Tumor mutational burden as a determinant of metastatic dissemination patterns
Molecular Oncology, EarlyView.This study performed a comprehensive analysis of genomic data to elucidate whether metastasis in certain organs share genetic characteristics regardless of cancer type. No robust mutational patterns were identified across different metastatic locations and cancer types.
Eduardo Candeal +4 more
wiley +1 more source
Theoretical Computer Science, 1988 Linear logic [\textit{J.-Y. Girard}, ibid. 50, 1-102 (1987; Zbl 0625.03037)] provides a refinement of functional programming and suggests a new implementation technique, with the following features: - a synthesis of strict and lazy evaluation, - a clean semantics of side effects, - no garbage collector.
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Molecular Oncology, EarlyView.Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source