Results 101 to 110 of about 3,497,223 (309)
Inhibition of dipeptidyl peptidase 7 impairs lysophagy in LLOMe‐treated HepG2 cells
FEBS Letters, EarlyView.DPP7 inhibition delays ubiquitin‐dependent lysophagy by attenuating ubiquitin accumulation and the recruitment of SQSTM1 and LC3 to damaged lysosomes, resulting in delayed clearance of damaged lysosomes and impaired restoration of lysosomal homeostasis. Created using FigureLabs (Certificate ID: FL‐PUB‐20260922‐Z99XNX).
Na Yeon Park +8 more
wiley +1 more source
Hierarchical Distributed Motion Control for Multiple Linear Switched Reluctance Machines
Energies, 2017 This paper investigates a distributed, coordinated motion control network based on multiple direct-drive, linear switched reluctance machines (LSRMs). A hierarchical, two-level synchronization control strategy is proposed for the four LSRMs based motion ...
Bo Zhang +5 more
doaj +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Chunking for Massive Nonlinear Kernel Classification [PDF]
, 2006 A chunking procedure [2] utilized in [18] for linear classifiers is proposed here for nonlinear kernel classification of massive datasets. A highly accurate algorithm based on nonlinear support vector machines that utilizes a linear programming ...
Mangasarian, Olvi, Thompson, Michael
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Stanford Linear Accelerator Center Annual Environmental Monitoring Report, January--December 1989
, 1990 This progress report discusses environmental monitoring activities at the Stanford Linear Accelerator Center for 1989. Topics include climate, site geology, site water usage, land use, demography, unusual events or releases, radioactive and ...
Stanford Linear Accelerator Center
core +1 more source
Homomorphic images of linear sequential machines [PDF]
, 1967 In this paper we investigate homomorphisms on the state behavior of linear machines and characterize their homomorphic images. These results are then applied to characterize those nonlinear machines which can be realized by larger linear ...
Wayne A. Davis +3 more
core +1 more source
Molecular Oncology, EarlyView.RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner +14 more
wiley +1 more source
Cluster based training for scaling non-linear support vector machines
, 2007 Support Vector Machines(SVMs) are hyperplane classifiers defined in a kernel induced feature space. The data size dependent training time complexity of SVMs usually prohibits its use in applications involving more than a few thousands of data points. In
Murty, M Narasimha +2 more
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Molecular Oncology, EarlyView.This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source
Semismooth Support Vector Machines [PDF]
, 2000 The linear support vector machine can be posed as a quadratic pro- gram in a variety of ways. In this paper, we look at a formulation using the two-norm for the misclassi cation error that leads to a positive de - nite quadratic program with a single ...
Ferris, Michael, Munson, Todd
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