Results 101 to 110 of about 2,479,210 (291)

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

Bayes factor for linear mixed model in genetic association studies

open access: yesQuantitative Biology
Bayes factor has advantages over p‐value as test statistics for association, particularly when comparing multiple non‐nested alternative models.
Yongtao Guan, Daniel Levy
doaj   +1 more source

Covariate Screening in Mixed Linear Models

open access: yesJournal of Multivariate Analysis, 1996
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
Welsh, Alan, Richardson, Alice
openaire   +3 more sources

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Estimation of genetic parameters in rubber progenies

open access: yesCrop Breeding and Applied Biotechnology, 2012
This study was designed to evaluate the genetic variability, the potential for rubber yield and secondary traits of rubber tree progenies at three locations in the state of Sao Paulo.
Cecília Khusala Verardi   +3 more
doaj  

Effect of the FGF2 SNP11646 on milk production and fertility traits of Holstein cattle

open access: yesCzech Journal of Animal Science, 2016
The objective of this study was to estimate the effect of a single-nucleotide polymorphism (SNP11646) in the FGF2 (Fibroblast Growth Factor 2) gene on the deregressed proof of breeding values (DRP) of Holstein sires (n = 149) for milk traits (milk yield,
M. Brzáková   +5 more
doaj   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

open access: yesFEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz   +11 more
wiley   +1 more source

Understory effect on tree and cork growth in cork oak woodlands

open access: yesForest Systems, 2018
Aim of study: Cork oak is one of the main forest tree species in Portugal that typically occurs in montado, where operational practices oriented to the tree, crop or animal management may influence several of the ecosystem components. This study aimed at
Sonia P. Faias   +3 more
doaj   +1 more source

Linear mixed models with endogenous covariates: modeling sequential treatment effects with application to a mobile health study

open access: yes, 2019
Mobile health is a rapidly developing field in which behavioral treatments are delivered to individuals via wearables or smartphones to facilitate health-related behavior change.
Klasnja, Predrag   +2 more
core  

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

open access: yesFEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

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