Results 111 to 120 of about 18,112,323 (302)

Linguistic pitch analysis using functional principal component mixed effect models [PDF]

open access: yes, 2009
Fundamental frequency (F0, broadly 'pitch') is an integral part of spoken human language; however, a comprehensive quantitative model for F0 can be a challenge to formulate owing to the large number of effects and interactions between effects that lie ...
Aston, John A. D.   +5 more
core   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

open access: yesFEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta   +3 more
wiley   +1 more source

Diagnostics for generalised linear mixed models [PDF]

open access: yes
Generalized linear mixed models are generalized linear models that include random effects varying between clusters or 'higher-level' units of hierarchically structured data. Such models can be estimated using gllamm.
Sophia Rabe-Hesketh, Anders Skrondal
core  

Balancing model of a flexible mixed model assembly line with feeder lines [PDF]

open access: yes, 2022
openStudiare/bilanciare linee di assemblaggio mixed-model con feeder ...
SAWIRES, JOHN NASRY SHOUKRY EBRAHIM
core  

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

open access: yesFEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg   +14 more
wiley   +1 more source

Mixed-effects model results.

open access: yes, 2016
In (a), the models study the effect of session length on the quality of the first comment C1 in a session; i.e., data only contains the first session comments.
Farshad Kooti (3080265)   +4 more
core   +1 more source

Genetic heterogeneity of residual variance - estimation of variance components using double hierarchical generalized linear models [PDF]

open access: yes, 2010
Background The sensitivity to microenvironmental changes varies among animals and may be under genetic control. It is essential to take this element into account when aiming at breeding robust farm animals.
Erling Strandberg   +21 more
core   +1 more source

Nutrient/TOR signaling controls adipose mitochondrial transcription factor A (TFAM) to regulate organismal growth in Drosophila

open access: yesFEBS Letters, EarlyView.
Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas   +4 more
wiley   +1 more source

OLS Estimator for a Mixed Regressive, Spatial Autoregressive Model: Extended Version [PDF]

open access: yes
We find the asymptotic distribution of the OLS estimator of the parameters $% \beta$ and $\rho$ in the mixed spatial model with exogenous regressors $% Y_n=X_n\beta+\rho W_nY_n+V_n$.
Mynbaev, Kairat
core  

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

open access: yesFEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt   +8 more
wiley   +1 more source

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