Results 81 to 90 of about 2,452,838 (337)

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

FEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva, Puspa Kunwar, Md Ibnul Rifat Rahman, Joanna Koryo Kwao, Nathan Lehman, Zihan Zhang, Trenton Paul, Claire Cheng, Nicholas Truex, Hui‐Ting Lee, Jun Zhang   +10 more
wiley   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

FEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li, Pedro A. Sánchez‐Murcia, Bernd Nidetzky   +2 more
wiley   +1 more source

Linear Mixed-Effects Model to Quantify the Association between Somatic Cell Count and Milk Production in Italian Dairy Herds [PDF]

, 2022
Tiantian Luo, W. Steeneveld, M. Nielen, Lucio Zanini, Alfonso Zecconi   +4 more
openalex   +1 more source

PICALM::MLLT10 translocated leukemia

FEBS Letters, EarlyView.
This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen, Antonia C. Nakatsugawa, Natalie Barton, Henry Haines, Gary S. Stein, Janet L. Stein, Daniel S. Wechsler, Jessica L. Heath   +7 more
wiley   +1 more source

Correction: Quantifier spreading: Children misled by ostensive cues

Glossa, 2019
This article details a correction to the article É. Kiss, Katalin & Tamás Zétényi. 2017. Quantifier spreading: children misled by ostensive cues. Glossa: A Journal of General Linguistics 2(1). 38.
Katalin É. Kiss, Katalin Mády, Tamás Zétényi   +2 more
doaj   +2 more sources

An investigation on the best-fit models for sugarcane biomass estimation by linear mixed-effect modelling on unmanned aerial vehicle-based multispectral images: A case study of Australia

, 2022
Sharareh Akbarian, Cheng‐Yuan Xu, Weijin Wang, Stephen Ginns, Samsung Lim   +4 more
openalex   +1 more source

Linear mixed models with endogenous covariates: modeling sequential treatment effects with application to a mobile health study

, 2019
Mobile health is a rapidly developing field in which behavioral treatments are delivered to individuals via wearables or smartphones to facilitate health-related behavior change.
Klasnja, Predrag, Murphy, Susan A., Qian, Tianchen   +2 more
core  

Mixed semi-Lagrangian/finite difference methods for plasma simulations [PDF]

, 2014
In this paper, we present an efficient algorithm for the long time behavior of plasma simulations. We will focus on 4D drift-kinetic model, where the plasma's motion occurs in the plane perpendicular to the magnetic field and can be governed by the 2D ...
Filbet, Francis, Yang, Chang
core   +2 more sources

Cell wall target fragment discovery using a low‐cost, minimal fragment library

FEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan, Mathew Stanley, Olawale Raimi, Andrew T. Ferenbach, Helge C Dorfmueller, Daan M. F. van Aalten   +5 more
wiley   +1 more source

Experimental Effects and Individual Differences in Linear Mixed Models: Estimating the Relation of Spatial, Object, and Attraction Effects in Visual Attention

Frontiers in Psychology, 2011
Linear mixed models (LMMs) provide a still underused methodological perspective on combining experimental and individual-differences research. Here we illustrate this approach with two-rectangle cueing in visual attention (Egly, Driver, & Rafal, 1994)
Reinhold Kliegl, Ping eWei, Michael Dambacher, Ming Yan, Ming Yan, Xiaolin Zhou   +5 more
doaj   +1 more source