Results 21 to 30 of about 68,721,496 (226)
Some Inequalities of the Gruss Type for the Numerical Radius of Bounded Linear Operators in Hilbert Spaces [PDF]
Some inequalities of the Gr¨ uss type for the numerical radius of bounded linear operators in Hilbert spaces are ...
S. S. Dragomir +2 more
core +1 more source
Diversity and complexity in neural organoids
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley +1 more source
Some New Grüss' Type Inequalities for Functions of Selfadjoint Operators in Hilbert Spaces [PDF]
Some new inequalities of Grüss’ type for functions of selfadjoint operators in Hilbert spaces, under suitable assumptions for the involved operators, are given.
Dragomir, Sever S
core +5 more sources
Remarks on Duality in Graph Spaces of First‐Order Linear Operators [PDF]
AbstractGraph spaces provide a setting alternative to Sobolev spaces and BV spaces, which is suitable for the analysis of first‐order linear boundary value problems such as Friedrichs systems. Besides investigations of the well‐posedness of the continuous problem there is also an increasing interest in the error analysis of finite element methods ...
openaire +2 more sources
Modelling stem cell differentiation related processes—A practical overview for biologists
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar +4 more
wiley +1 more source
Design and analysis strategies for robust microbiome ageing research
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
Reconstructing enzyme evolution by protein engineering
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Linear differential equations of higher orders in a Banach space and the Vandermonde operator
Summary: We study the question of existence of a unique bounded solution to a Cauchy problem for a higher-order differential equation with bounded operator coefficients. The case under consideration is where the corresponding `algebraic' operator equation has separated pairwise commuting roots. Using the Vandermonde operator constructed from such roots,
openaire +2 more sources
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source

