Results 21 to 30 of about 68,721,496 (226)

Some Inequalities of the Gruss Type for the Numerical Radius of Bounded Linear Operators in Hilbert Spaces [PDF]

open access: yes, 2008
Some inequalities of the Gr¨ uss type for the numerical radius of bounded linear operators in Hilbert spaces are ...
S. S. Dragomir   +2 more
core   +1 more source

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

open access: yesFEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

Some New Grüss' Type Inequalities for Functions of Selfadjoint Operators in Hilbert Spaces [PDF]

open access: yes, 2008
Some new inequalities of Grüss’ type for functions of selfadjoint operators in Hilbert spaces, under suitable assumptions for the involved operators, are given.
Dragomir, Sever S
core   +5 more sources

Remarks on Duality in Graph Spaces of First‐Order Linear Operators [PDF]

open access: yesPAMM, 2006
AbstractGraph spaces provide a setting alternative to Sobolev spaces and BV spaces, which is suitable for the analysis of first‐order linear boundary value problems such as Friedrichs systems. Besides investigations of the well‐posedness of the continuous problem there is also an increasing interest in the error analysis of finite element methods ...
openaire   +2 more sources

Modelling stem cell differentiation related processes—A practical overview for biologists

open access: yesFEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar   +4 more
wiley   +1 more source

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

Linear differential equations of higher orders in a Banach space and the Vandermonde operator

open access: yesMethods of Functional Analysis and Topology, 2022
Summary: We study the question of existence of a unique bounded solution to a Cauchy problem for a higher-order differential equation with bounded operator coefficients. The case under consideration is where the corresponding `algebraic' operator equation has separated pairwise commuting roots. Using the Vandermonde operator constructed from such roots,
openaire   +2 more sources

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

open access: yesFEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta   +3 more
wiley   +1 more source

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