Results 41 to 50 of about 1,026 (231)

Linear differential equations of higher orders in a Banach space and the Vandermonde operator

Methods of Functional Analysis and Topology, 2022
Summary: We study the question of existence of a unique bounded solution to a Cauchy problem for a higher-order differential equation with bounded operator coefficients. The case under consideration is where the corresponding `algebraic' operator equation has separated pairwise commuting roots. Using the Vandermonde operator constructed from such roots,
openaire   +2 more sources

Ideal points in multiobjective programming [PDF]

, 1993
The main object of this paper is to give conditions under which a minimal solution to a problem of mathematical programming can be transformed into a minimum solution in the usual sense of the order relations, or in every case, conditions under which ...
Balbás, Alejandro, Jiménez Guerra, Pedro, Núñez, Carmelo   +2 more
core  

The linear quadratic regulator problem for a class of controlled systems modeled by singularly perturbed Ito differential equations

, 2012
Link to a related website: https://digital.library.adelaide.edu.au/dspace/bitstream/2440/77907/1/hdl_77907.pdf, Open Access via UnpaywallThis paper discusses an infinite-horizon linear quadratic (LQ) optimal control problem involving state- and control ...
Shi, Peng, Mukaidani, Hiroaki, Dragan, V., Mukaidani, H., Dragan, Vasile, Shi, P.   +5 more
core   +1 more source

An unexpected alternative viologen electron mediator site in tungsten‐containing formate dehydrogenase

FEBS Letters, EarlyView.
An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley   +1 more source

Existence of positive solutions for half-linear fractional order BVPs by application of mixed monotone operators

, 2020
In this paper we developed tripled fixed point theorems of ternary operator on partially ordered metric spaces. As an application we established existence of positive solutions for half-linear fractional order boundary value problem.
K. R. Prasad, M. Khuddush, D. Leela
semanticscholar   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

A Full Space-Time Convergence Order Analysis of Operator Splittings for Linear Dissipative Evolution Equations [PDF]

Communications in Computational Physics, 2016
The Douglas--Rachford and Peaceman--Rachford splitting methods are common choices for temporal discretizations of evolution equations. In this paper we combine these methods with spatial discretizations fulfilling some easily verifiable criteria.
Hansen, Eskil, Henningsson, Erik
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Interpreting the effects of DNA polymerase variants at the structural level

Molecular Oncology, EarlyView.
Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi, Karolina Krzesińska, Ludovica Beltrame, Pablo Sánchez‐Izquierdo Besora, Matteo Tiberti, Mef Nilbert, Anna Rohlin, Elena Papaleo   +7 more
wiley   +1 more source

Third-Order Tensors as Linear Operators on a Space of Matrices

Linear Algebra and its Applications, 2010
AbstractA recently proposed tensor-tensor multiplication (M.E. Kilmer, C.D. Martin, L. Perrone, A Third-Order Generalization of the Matrix SVD as a Product of Third-Order Tensors, Tech. Rep. TR-2008-4, Tufts University, October 2008) opens up new avenues to understanding the action of n×n×n tensors on a space of n×n matrices.
openaire   +1 more source