Results 91 to 100 of about 383,425 (312)

OPTIMIZATION OF LINEAR HYBRID CONTROL SYSTEMS

open access: yesНаука и техника, 2007
A linear optimal control problem for a hybrid system is solved. The Cauchy formula is derived with its help the initial problem is reduced to a special linear programming.
O. R. Gabasova
doaj   +1 more source

Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells

open access: yesMolecular Oncology, EarlyView.
We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller   +17 more
wiley   +1 more source

LINC01116, a hypoxia‐lncRNA marker of pathological lymphangiogenesis and poor prognosis in lung adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
The LINC01116 long noncoding RNA is induced by hypoxia and associated with poor prognosis and high recurrence rates in two cohorts of lung adenocarcinoma patients. Here, we demonstrate that besides its expression in cancer cells, LINC01116 is markedly expressed in lymphatic endothelial cells of the tumor stroma in which it participates in hypoxia ...
Marine Gautier‐Isola   +12 more
wiley   +1 more source

COMTOP: Protein Residue-Residue Contact Prediction through Mixed Integer Linear Optimization. [PDF]

open access: yesMembranes (Basel), 2021
Reza MS   +5 more
europepmc   +1 more source

INTELLIGENT NETWORKED HYBRID ELECTRIC VEHICLE OPTIMIZATION USING A LINEARIZED ECMS CONTROL ALGORITHM

open access: bronze, 2021
Mengxiong Lu   +99 more
openalex   +1 more source

LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro

open access: yesMolecular Oncology, EarlyView.
Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix   +13 more
wiley   +1 more source

KAFA-Merge: Model Merging Method With Layer-Based Bayes+Linear Search

open access: yesIEEE Access
In this paper, we consider the model merging process for large language models (LLMs) under a two-stage optimization framework. Traditional merging methods usually apply fixed blending rates to all layers, which ignores the different levels of ...
Muzaffer Kaan Yuce   +1 more
doaj   +1 more source

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