Results 111 to 120 of about 5,705,352 (293)

Comparison of Robust and Varying Parameter Estimates of a Macroeconometric Model [PDF]

Four estimators of econometric models are compared for predictive accuracy. Two estimators assume that the parameters of the equations are subject to variation over time.
Thomas F. Cooley
core  

Linear Time-Varying Logistic Model With Shape Parameter for Dynamic Epidemic Modeling

Journal of Applied Mathematics
We propose extending the logistic growth model by introducing a Linear Time-Varying Logistic Model with Shape Parameter (LTVLMS). This model incorporates a time-varying linear growth rate function, rt=r0+r1t, along with a shape parameter ν to allow for ...
Redouane Betrouni, Tewfik Kernane
doaj   +1 more source

Genetic algorithm–based varying parameter linear quadratic regulator control for four-wheel independent steering vehicle

Advances in Mechanical Engineering, 2015
From the perspective of vehicle dynamics, the four-wheel independent steering vehicle dynamics stability control method is studied, and a four-wheel independent steering varying parameter linear quadratic regulator control system is proposed with the ...
Linlin Gao, Lisheng Jin, Faji Wang, Yi Zheng, Keyong Li   +4 more
doaj   +1 more source

Flow Enabled Target Capture Halbach‐based magnetic enrichment increases circulating tumor cell capture from blood in metastatic cancer patients

Molecular Oncology, EarlyView.
Pair‐wise comparison of the CellSearch and FETCH enrichment technologies for circulating tumor cells (CTCs) from metastatic breast, prostate, and small cell lung cancer patients shows an increased capture of CTCs using FETCH enrichment. The clinical implementation of circulating tumor cells (CTCs) as a predictive tool for therapy efficacy in the ...
Michiel Stevens, Anouk Mentink, Tom Niessink, Frank Coumans, Leonie Mekenkamp, Ruchi Bansal, Jeroen Hiltermann   +6 more
wiley   +1 more source

Parameter Instability and Forecasting Performance. A Monte Carlo Study [PDF]

This paper uses Monte Carlo techniques to assess the loss in terms of forecast accuracy which is incurred when the true DGP exhibits parameter instability which is either overlooked or incorrectly modelled.
Pittis, Nikitas, Anyfantakis, Costas, Caporale, Guglielmo M.   +2 more
core  

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

Molecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka, Wioleta Cieślik, Wojciech Płaziński, Katarzyna Stępnik, Anna Boguszewska‐Czubara, Elżbieta Kot, Robert Musioł, Mateusz Jasica, Anna Mrozek‐Wilczkiewicz, Katarzyna Malarz   +9 more
wiley   +1 more source

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

Molecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur, Joel Rodrigues Vitória, Manuel Saiselet, Ligia Craciun, Denis Larsimont, Anne Lefort, Frédérick Libert, Carine Maenhaut, Sabine Costagliola, Maxime Tarabichi, Mirian Romitti, Vincent Detours   +11 more
wiley   +1 more source

Inhibition of cyclin‐dependent kinases 12/13 using CT7439 as a treatment for colorectal cancer with CDK12 upregulation

Molecular Oncology, EarlyView.
The proposed mechanism of action for the CDK12/13 inhibitor and cyclin K degrader, CT7439. CDK12/13 inhibition interrupts transcription elongation, leading to increased DNA damage that results in cell death. This agent is a potentially novel treatment option for patients with colorectal cancer. Created in BioRender. Cyclin‐dependent kinase (CDK) 12 and
Wylie K. Watlington, Divya L. Dayanidhi, Mohammad Zokaasadi, John B. Mantyh, Pelumi D. Olawuni, Gabrielle Rupprecht, Jeremy M. Force, Shannon McCall, Ashwani K. Bahl, David S. Hsu, Jason A. Somarelli   +10 more
wiley   +1 more source

Linear, Parameter-Varying Control of Aeroservoelastic Systems [PDF]

, 2015
University of Minnesota Ph.D. dissertation. June 2015. Major: Aerospace Engineering and Mechanics. Advisor: William Garrard. 1 computer file (PDF); xiii, 131 pages.Modern aircraft designers are adopting light-weight, high-aspect ratio flexible wings to
Moreno Chicunque, Claudia
core  

Rotorcraft vibration control: adaptive vs LPV methods

, 2015
This paper proposes a parameter-varying approach for the vibration control problem in rotorcraft applications. The proposed algorithm can be considered as a variant of Harmonic Control (HC), and can be placed beside existing adaptive versions used in the
MURA, ROBERTO, LOVERA, MARCO
core   +1 more source