Results 91 to 100 of about 163,783 (268)

Identification of the plant mitochondrial OrfX protein: A mass spectrometry approach

open access: yesFEBS Letters, EarlyView.
The mitochondrial genome of plants contains an open reading frame, orfx, which encodes a rare protein that has so far escaped mass spectrometric detection. The protein resembles the c‐subunit of bacterial twin‐arginine‐motif‐dependent protein translocases (TatC).
Matthias Döring   +3 more
wiley   +1 more source

Robust Time-Varying Parameter Estimation of Uncertain LPV Systems Subject to Estimated States

open access: yesIEEE Access
In recent years, many techniques for parameter estimation have been developed, with special attention given to the case of time-varying parameters, as they can describe a wide range of physical systems.
Esdras Battosti Da Silva   +4 more
doaj   +1 more source

New Delay-Dependent Robust Exponential Stability Criteria of LPD Neutral Systems with Mixed Time-Varying Delays and Nonlinear Perturbations

open access: yesJournal of Applied Mathematics, 2013
This paper is concerned with the problem of robust exponential stability for linear parameter-dependent (LPD) neutral systems with mixed time-varying delays and nonlinear perturbations.
Sirada Pinjai, Kanit Mukdasai
doaj   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

open access: yesMolecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla   +9 more
wiley   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch   +13 more
wiley   +1 more source

On The Design and Characteristics of a Sub-Optimal Observer for Boeing-747

open access: yesMehran University Research Journal of Engineering and Technology, 2018
LPV (Linear Parameter Varying) system is an important class of system, as it covers many physical systems. In the existing design theory related to control system, the major part is related to linear and non-linear systems.
Wasiullah Khan   +2 more
doaj   +1 more source

Annihilator design for linear parameter varying systems

open access: yesIFAC-PapersOnLine, 2018
Abstract Computation of the annihilator of a linear parameter-dependent (LPV) dynamical system is an important subtask in several fields of control theory, such as fault detection design or reconfigurable control design. While for LTI systems the problem can be efficiently handled, for LPV systems is not available a single algorithm that would ...
Szabó, Z., Péni, T., Bokor, J.
openaire   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

Robust Quasi–LPV Model Reference FTC of a Quadrotor Uav Subject to Actuator Faults

open access: yesInternational Journal of Applied Mathematics and Computer Science, 2015
A solution for fault tolerant control (FTC) of a quadrotor unmanned aerial vehicle (UAV) is proposed. It relies on model reference-based control, where a reference model generates the desired trajectory.
Rotondo Damiano   +2 more
doaj   +1 more source

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

open access: yesMolecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan   +16 more
wiley   +1 more source

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