Results 81 to 90 of about 13,562,447 (238)
Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network
FEBS Letters, EarlyView.Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley +1 more source
Parameter identification and hybrid mathematical modelling techniques applied to non-linear control systems [PDF]
The study is concerned with the mathematical modelling and parameter identification of nonlinear motion control systems. The control systems under review are the axis motion control systems for a 3-axis CNC machine tool.
Pislaru, Crinela
core +4 more sources
Journal of Applied Mathematics, 2014 A new periodic recursive least-squares (PRLS) estimator is developed with data-weighting factors for a class of linear time-varying parametric systems where the uncertain parameters are periodic with a known periodicity.
Ronghu Chi, Zhongsheng Hou, Shangtai Jin
doaj +1 more source
Dual MPC for quasi-Linear Parameter Varying systems
CoRR9 pages, 1 ...
Sampath Kumar Mulagaleti +1 more
openaire +2 more sources
FEBS Letters, EarlyView.Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante +10 more
wiley +1 more source
Linear Parameter Varying Representation of a class of MIMO Nonlinear Systems
IFAC-PapersOnLine, 2018 Linear parameter-varying (LPV) models form a powerful model class to analyze and control a (nonlinear) system of interest. Identifying an LPV model of a nonlinear system can be challenging due to the difficulty of selecting the scheduling variable(s) a priori, especially if a first principles based understanding of the system is unavailable. Converting
Schoukens, Maarten, Tóth, Roland
openaire +3 more sources
Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
FEBS Letters, EarlyView.EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
AxiomsThis paper proposes a data-driven control design framework for linear parameter-varying (LPV) systems with polyhedral and ellipsoidal constraints, where the input matrix of the system is constant.
Hongli Yang +2 more
doaj +1 more source
International Journal of Aerospace Engineering, 2019 Robust H∞ consensus control problems of linear swarm systems with parameter uncertainties and time-varying delays are investigated. In this literature, a linear consensus protocol for high-order discrete-time swarm systems is proposed.
Xiao Jia, Laihong Hu, Fujun Feng, Jun Xu
doaj +1 more source
Emerging experimental and computational methods for studying redox‐regulated structural transitions
FEBS Letters, EarlyView.Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source