Results 71 to 80 of about 13,562,447 (237)

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

open access: yesFEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang   +4 more
wiley   +1 more source

New Delay-Dependent Robust Stability Criterion for LPD Discrete-Time Systems with Interval Time-Varying Delays

open access: yesDiscrete Dynamics in Nature and Society, 2013
This paper investigates the problem of robust stability for linear parameter-dependent (LPD) discrete-time systems with interval time-varying delays. Based on the combination of model transformation, utilization of zero equation, and parameter-dependent ...
Narongsak Yotha, Kanit Mukdasai
doaj   +1 more source

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

open access: yesFEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg   +14 more
wiley   +1 more source

Functional Interval Observers-Based Active Fault Tolerant Control for Continuous-Time Linear Parameter-Varying Systems

open access: yesIEEE Access
This article addresses the problem of Functional Interval Observers (FIO) based on Active Fault Tolerant Control for continuous-time polytopic Linear Parameter-Varying systems in the presence of unknown but bounded uncertainties, external disturbances ...
Hanin Mizouri   +2 more
doaj   +1 more source

Control of Nonlinear Distributed Parameter Systems Based on Global Approximation

open access: yesJournal of Applied Mathematics, 2014
We extend an iterative approximation method to nonlinear, distributed parameter systems given by partial differential and functional equations. The nonlinear system is approached by a sequence of linear time-varying systems, which globally converges in ...
Chunyan Du, Guansheng Xing
doaj   +1 more source

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

open access: yesFEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt   +8 more
wiley   +1 more source

Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network

open access: yesFEBS Letters, EarlyView.
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley   +1 more source

Parameter identification and hybrid mathematical modelling techniques applied to non-linear control systems [PDF]

open access: yes
The study is concerned with the mathematical modelling and parameter identification of nonlinear motion control systems. The control systems under review are the axis motion control systems for a 3-axis CNC machine tool.
Pislaru, Crinela
core   +4 more sources

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

open access: yesFEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante   +10 more
wiley   +1 more source

Data-Weighting Periodic RLS Based Adaptive Control Design and Analysis without Linear Growth Condition

open access: yesJournal of Applied Mathematics, 2014
A new periodic recursive least-squares (PRLS) estimator is developed with data-weighting factors for a class of linear time-varying parametric systems where the uncertain parameters are periodic with a known periodicity.
Ronghu Chi, Zhongsheng Hou, Shangtai Jin
doaj   +1 more source

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