Results 81 to 90 of about 1,050,980 (296)

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

FEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

A Joint Compensation Method for Repositioning Error and Atmospheric Phase Screen of Ground-Based SAR

IEEE Journal of Selected Topics in Applied Earth Observations and Remote Sensing
In the monitoring of discontinuous ground-based synthetic aperture radar (GB-SAR), challenges such as repositioning error and atmospheric phase screen (APS) can significantly impact the accuracy of deformation inversion. Existing compensation methods are
Zechao Bai, Peng Cui, Yanping Wang, Hui Liu, Yun Lin, Yang Li, Wenjie Shen   +6 more
doaj   +1 more source

Estimating CDM Particle Trajectories in the Mildly Non-Linear Regime of Structure Formation. Implications for the Density Field in Real and Redshift Space

, 2013
We obtain approximations for the CDM particle trajectories starting from Lagrangian Perturbation Theory. These estimates for the CDM trajectories result in approximations for the density in real and redshift space, as well as for the momentum density ...
H.-J. Seo ., Matias Zaldarriaga, P. Catelan, S. Tassev, S. Tassev, S. Tassev, SDSS collaboration, Svetlin Tassev, U. Seljak, Y. Zel'dovich   +9 more
core   +1 more source

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

Molecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice, Jose I. Lopez, Aitziber Ugalde‐Olano, Maite Zufiaurre, Ianire Astobiza, Natalia Martin‐Martin, Laura Bozal‐Basterra, Saioa Garcia‐Longarte, Amaia Zabala‐Letona, Sofia Rey, Aida Santos‐Martin, Miguel Unda, Ana Loizaga‐Iriarte, Mariona Graupera, Paolo Nuciforo, Arkaitz Carracedo, Isabel Mendizabal   +16 more
wiley   +1 more source

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon, Peter T. Gallagher, Orly I. Richter, Neermala Poudel Neupane, Amy C. Mandigo, Jennifer J. McCann, Emanuela Dylgjeri, Irina Vasilevskaya, Christopher McNair, Channing J. Paller, Wm. Kevin Kelly, Karen E. Knudsen, Matthew J. Schiewer, Ayesha A. Shafi   +13 more
wiley   +1 more source

Non-dispersive wavepackets generated in layered structures by a scanning laser source

AIP Advances, 2020
In this article, we describe the use of a continuous-wave laser scanning method to generate non-dispersive surface acoustic wavepackets, which propagate along the sample surface without any waveform change.
Zheng Li, Zhonghua Shen, Sridhar Krishnaswamy   +2 more
doaj   +1 more source

Single Channel Josephson Effect in a High Transmission Atomic Contact

, 2018
The Josephson effect in scanning tunneling microscopy (STM) is an excellent tool to probe the properties of the superconducting order parameter on a local scale through the Ambegaokar-Baratoff (AB) relation.
Ankerhold, Joachim, Ast, Christian R., Belzig, Wolfgang, Cuevas, Juan Carlos, Dambach, Simon, Drost, Robert, Etzkorn, Markus, Kern, Klaus, Kubala, Björn, Padurariu, Ciprian, Senkpiel, Jacob, Yeyati, Alfredo Levy   +11 more
core   +1 more source

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

Molecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla, Jan Kosla, Magdalena Prechova, Lukas Frick, Patricia Bortel, Yasmin Borutzki, Andrea Bileck, Christopher Gerner, Samuel M. Meier‐Menches, Selma Osmanagic‐Myers, Martin Gregor   +10 more
wiley   +1 more source

One microwave imaging system based on automotive radar chip

The Journal of Engineering, 2019
The interest in microwave imaging system is increasing because it can serve as a useful tool for concealed threat detecting. The current imaging systems have two major challenges: (i) multi-static arrays suffer from complex hardware design and ...
Fuwei Wu, Siming Li, Shize Shang, Yuanji Li, Yuhao Yang   +4 more
doaj   +1 more source

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

Molecular Oncology, EarlyView.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff, Manuela Moritz, Dennis Eggert, Anna Worthmann, Joerg Heeren, Henrike Zech, Till S. Clauditz, Waldemar Wilczak, Hartmut Schlüter, Christian S. Betz, Arne Böttcher, Jan Hahn   +11 more
wiley   +1 more source