Results 81 to 90 of about 427,856 (306)

One microwave imaging system based on automotive radar chip

The Journal of Engineering, 2019
The interest in microwave imaging system is increasing because it can serve as a useful tool for concealed threat detecting. The current imaging systems have two major challenges: (i) multi-static arrays suffer from complex hardware design and ...
Fuwei Wu, Siming Li, Shize Shang, Yuanji Li, Yuhao Yang   +4 more
doaj   +1 more source

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

Molecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan, Veronika M Metzler, Simone de Brot, Corinne L Woodcock, Anna E Harris, Jennifer Lothion‐Roy, Emeli M Nilsson, Atara Ntekim, Michael S Toss, Jenny L Persson, Francesca Khani, Brian D Robinson, Lorraine J Gudas, Emad Rakha, David M Heery, Catrin S Rutland, Nigel P Mongan   +16 more
wiley   +1 more source

Heterozygous loss‐of‐function alleles associate the conserved 3′‐5′ exoribonuclease EXOSC10 with hypersensitivity to the anticancer drug 5‐fluorouracil

Molecular Oncology, EarlyView.
EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain, Yann Le Page, Frédéric Percevault, Emmanuelle Becker, Luc Negroni, Almudena Fernandez, Marta Cantero, Diego Muñoz‐Santos, Lluís Montoliu, Cyrille Garnier, Michael Primig   +10 more
wiley   +1 more source

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

Molecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner, Pierre Tennstedt, Randi C. Pose, Christian Müller, Katharina Besler, Svenja Schneegans, Malik Alawi, Marie C. Roesch, Sven Peine, Desiree Bonci, Joanna Budna‐Tukan, Evi Lianidou, Catherine Alix‐Panabières, Derya Tilki, Klaus Pantel   +14 more
wiley   +1 more source

Scanning electrochemical microscopy for the characterisation of surfaces modified with biological molecules [PDF]

, 2011
This thesis describes a novel fabrication procedure for microelectrodes to be used with the scanning electrochemical microscope (SECM), the characterisation of a variety of novel impedance based immunosensors, and the characterisation of a novel ...
Holmes, Joanne L.
core  

Integrated circuits of self-scanning linear photodetectors in introscopy and tomography

Технологія та конструювання в електронній апаратурі, 2005
The results of designing and the characteristics of linear photosensitive devices (LPDs) based on active sensor cells and digital polling registers are presented.
V. L. Perevertaylo, A. A. Epifanov, V. G. Karengin, L. I. Таrаsеnkо, V. G. Karengin   +4 more
doaj  

The Influence of Process Parameters on the Density, Microstructure, and Mechanical Properties of TA15 Titanium Alloy Fabricated by Selective Laser Melting

Metals
With superior manufacturing freedom capability, Selective Laser Melting (SLM) technology is capable of fabricating high-strength Ti-6Al-2Zr-1Mo-1V (TA15) complex titanium alloy parts, thereby finding extensive applications in the aerospace sector.
Junjie Jiang, Chuang Liang, Yuanchao Chen, Yongbiao Wang, Hongyang Cui, Jianlin Xu, Fang Zhou, Pengpeng Wang, David Z. Zhang   +8 more
doaj   +1 more source

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

Molecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena, Karin Teien Lande, Eva Diaz, Ana Vilar, Juan Cueva, Efigenia Arias, Victoria Sampayo, Alicia Abalo, Nerea González, Eva Colás, Antonio Gil‐Moreno, Miguel Abal, Gema Moreno‐Bueno, Therese Sørlie, Kristina Lindemann, Laura Muinelo‐Romay   +15 more
wiley   +1 more source

Coherent microscopy and optical coherence tomography for biomedical applications

, 2011
This paper was presented at the 3rd Micro and Nano Flows Conference (MNF2011), which was held at the Makedonia Palace Hotel, Thessaloniki in Greece.
Coupland, JM, 3rd Micro and Nano Flows Conference (MNF2011)   +1 more
core  

Distribution-free specification tests of conditional models [PDF]

, 2008
This article proposes a class of asymptotically distribution-free specification tests for parametric conditional distributions. These tests are based on a martingale transform of a proper sequential empirical process of conditionally transformed data ...
Delgado, Miguel A., Stute, Winfried
core   +1 more source