Results 101 to 110 of about 5,217,955 (289)
FEBS Letters, EarlyView.Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson +7 more
wiley +1 more source
Haefliger structures and linear homotopy [PDF]
Transactions of the American Mathematical Society, 1984 The notion of linear-homotopy into a classifying space is introduced and used to give a precise classification of Haefliger structures. Appendix on the product theorem for simplicial spaces and realizations of bisimplicial spaces.
openaire +2 more sources
FEBS Letters, EarlyView.We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
wiley +1 more source
Bifurcation Structure in a Bimodal Piecewise Linear Business Cycle Model
Abstract and Applied Analysis, 2014 We study the bifurcation structure of the parameter space of a 1D continuous piecewise linear bimodal map which describes dynamics of a business cycle model introduced by Day-Shafer. In particular, we obtain the analytical expression of the boundaries of
Viktor Avrutin +2 more
doaj +1 more source
Structural biology of ferritin nanocages
FEBS Letters, EarlyView.Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley +1 more source
Non-Linear Seismic Analysis Method of Concrete Frame Structure [PDF]
Bulletin of the Polytechnic Institute of Jassy: Constructions, Architechture Section, 2005 The proposed computation method principle utilized in the studied problem, which consist in solving the dynamic equilibrium differential equation system, written in the incremental form, using a hysteretic model of computing in analytical form, is ...
V. Filip, Felix Schärf
doaj
FEBS Letters, EarlyView.In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai +9 more
wiley +1 more source
FEBS Letters, EarlyView.Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes +4 more
wiley +1 more source
Calpain small subunit homodimerization is robust and calcium‐independent
FEBS Letters, EarlyView.Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
STRUCTURAL LINEARITY AND NON-LINEARITY. [PDF]
International Journal of Advanced Research, 2017 VaibhvP Karnik +2 more
openaire +1 more source