Phosphatidic acid directly activates mTOR and then regulates SREBP to promote ganoderic acid biosynthesis under heat stress in Ganoderma lingzhi. [PDF]
Commun BiolLiu YN +6 more
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Artemether Attenuates High Glucose-Induced Inflammation and Fibrogenesis in Renal Tubular Epithelial Cells by Modulating the TGF-<i>β</i>/Smad Pathway Via PPAR<i>γ</i> Activation. [PDF]
J Diabetes ResZhang X +7 more
europepmc +1 more source
Mitigating Limited Data Challenges to Improve Artificial Intelligence Integration in Rare Disease Drug Development. [PDF]
NEJM AIPoddar A +7 more
europepmc +1 more source
Bioactive components and delivery strategies of food-medicine homologous substances in lung cancer therapy: current advances and clinical translation. [PDF]
Front NutrSun M, Zang D, Chen J.
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Cytotoxic ergostane-type steroids from Ganoderma lingzhi
Steroids, 2021Two new ergostane-type steroids (1 and 2) have been isolated from the fruiting body of a medicinal macro fungus Ganoderma lingzhi. The structures including the absolute configurations of them were elucidated by a combination of different spectroscopic analyses especially 13C NMR and ECD calculations. Compound 2 features an unusual 1,2-dioxolane moiety.
Hua Zhang
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This study aimed to obtain a set of specific inter simple sequence repeat (ISSR) primers and establish a stable and accurate intraspecific identification method for Ganoderma lingzhi. A total of 117 G. lingzhi strains were identified using internal transcribed spacer sequences from 147 strains determined as G.
Liming, He +4 more
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The transcriptome is the set of all RNA molecules in one cell or a population of cells. There are several different methods to obtain the transcriptome, including cDNA-amplified fragment length polymorphism (cDNA-AFLP), expressed sequence tags (EST), serial analysis of gene expression (SAGE), microarrays, and RNA-Seq.
Haimei Chen, Yang Ni, Heyu Yang
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Lingzhi mushroom refers to a group of fungal species belonging to the genus Ganoderma. During the past 10 years, the genetic studies of Lingzhi have made great strides. The nuclear and mitochondrial genomes of several Ganoderma species are publicly available. Transcriptome and proteome studies of Lingzhi have been described and reported.
Qing Du, Yuxin Cao, Chang Liu
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Methoxyflavones from New Lingzhi Medicinal Mushroom, Ganoderma lingzhi (Agaricomycetes)
International Journal of Medicinal Mushrooms, 2016Ganoderma lingzhi is one of the most famous medicinal fungi in the world. It has been used in folk medicine, especially in East Asian countries. It is also a white-rot fungus with strong wood degradation ability, especially against lignin. Different classes of bioactive natural products have been reported in Ganoderma, including triterpenes ...
Kuniyoshi, Shimizu +2 more
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