Results 141 to 150 of about 537,873 (344)
Abstract Objective The gut microbiota (GM) plays a role in epilepsy development via the microbiota–gut–brain axis. However, its relationship with various epilepsy subtypes and its mediating role through immune cells remain unclear. Thus, identifying the GM linked to specific epilepsy subtypes and investigating immune mechanisms to predict epilepsy risk,
Xu Zhang+4 more
wiley +1 more source
The causal relationship between gut microbiota and brain tumors and potential prognostic value of microbiota are still unclear. This study confirmed the causal effects of specific gut microbiota on three common brain tumors and identified microbe‐related genes that are expressed in brain tissue and correlated with the abundance of gut microbiota ...
Changwu Wu+7 more
wiley +1 more source
Linkage disequilibrium in growing and stable populations. [PDF]
Montgomery Slatkin
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This study comprehensively evaluated the differential effect of clonal hematopoiesis (CH) mutations on the risk of various stroke subtypes and functional recovery. It shows that TET2 is associated with small vessel stroke possibly via a pro‐inflammatory pathway. Abstract Recent observational studies have found an association between Clonal Hematopoesis
Shuyang Lin, Yang E. Li, Yan Wang
wiley +1 more source
Additional polymorphisms at marker loci D9S5 and D9S15 generate extended haplotypes in linkage disequilibrium with Friedreich ataxia. [PDF]
Ricardo Fujita+4 more
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Efficient estimation for large-scale linkage disequilibrium patterns of the human genome. [PDF]
Huang X+5 more
europepmc +1 more source
Extensive linkage disequilibrium in the achaete-scute complex of Drosophila melanogaster. [PDF]
J. Michael Macpherson+2 more
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Mendelian randomization (MR) studies were conducted using the inverse‐variance weighted (IVW) method, MR‐Egger and weighted median on juvenile myoclonic epilepsy (JME), and systemic lupus erythematosus (SLE) data from the Integrative Epidemiology Unit (IEU) Open genome‐wide association study (GWAS) database and the International League Against Epilepsy
Sirui Chen+10 more
wiley +1 more source
Linkage disequilibrium mapping in isolated populations: The example of Finland revisited [PDF]
Albert de la Chapelle, Fred A. Wright
openalex +1 more source
What's New? Fluoropyrimidines, a key component of chemotherapy regimens for a variety of solid tumors, can cause severe toxicity. Patients who have specific genetic variants in the DPYD gene, which encodes an enzyme that inactivates fluoropyrimidines, have increased susceptibility to this toxicity.
Sofía L. J. Peeters+12 more
wiley +1 more source