Results 41 to 50 of about 537,873 (344)

ngsLD: evaluating linkage disequilibrium using genotype likelihoods

open access: yesBioinform., 2019
MOTIVATION Linkage disequilibrium measures the correlation between genetic loci and is highly informative for association mapping and population genetics.
Emma A. Fox   +3 more
semanticscholar   +1 more source

Linkage Disequilibrium in Domestic Sheep [PDF]

open access: yesGenetics, 2002
Abstract The last decade has seen a dramatic increase in the number of livestock QTL mapping studies. The next challenge awaiting livestock geneticists is to determine the actual genes responsible for variation of economically important traits.
McRae, AF   +5 more
openaire   +3 more sources

Linkage disequilibrium fine mapping of quantitative trait loci: A simulation study

open access: yesGenetics Selection Evolution, 2003
Recently, the use of linkage disequilibrium (LD) to locate genes which affect quantitative traits (QTL) has received an increasing interest, but the plausibility of fine mapping using linkage disequilibrium techniques for QTL has not been well studied ...
Pérez-Enciso Miguel   +3 more
doaj   +1 more source

Most chromatin interactions are not in linkage disequilibrium

open access: yesGenome Research, 2019
Chromatin interactions and linkage disequilibrium (LD) are both pairwise measurements between genomic loci that show block patterns along mammalian chromosomes.
Sean Whalen, K. Pollard
semanticscholar   +1 more source

Characterization of genetic diversity and linkage disequilibrium of ZmLOX4 and ZmLOX5 loci in maize. [PDF]

open access: yesPLoS ONE, 2013
Maize (Zea mays L.) lipoxygenases (ZmLOXs) are well recognized as important players in plant defense against pathogens, especially in cross kingdom lipid communication with pathogenic fungi.
Gerald N De La Fuente   +6 more
doaj   +1 more source

Does probabilistic modelling of linkage disequilibrium evolution improve the accuracy of QTL location in animal pedigree?

open access: yesGenetics Selection Evolution, 2010
Background Since 2001, the use of more and more dense maps has made researchers aware that combining linkage and linkage disequilibrium enhances the feasibility of fine-mapping genes of interest.
Estivals Delphine   +8 more
doaj   +1 more source

Association testing strategy for data from dense marker panels. [PDF]

open access: yesPLoS ONE, 2013
Genome wide association studies have been usually analyzed in a univariate manner. The commonly used univariate tests have one degree of freedom and assume an additive mode of inheritance.
Donghyung Lee, Silviu-Alin Bacanu
doaj   +1 more source

Linkage disequilibrium dependent architecture of human complex traits reveals action of negative selection

open access: yesbioRxiv, 2016
Recent work has hinted at the linkage disequilibrium (LD) dependent architecture of human complex traits, where SNPs with low levels of LD (LLD) have larger per-SNP heritability after conditioning on their minor allele frequency (MAF).
S. Gazal   +10 more
semanticscholar   +1 more source

Whole genome genetic variation and linkage disequilibrium in a diverse collection of Listeria monocytogenes isolates.

open access: yesPLoS ONE, 2021
We performed whole-genome multi-locus sequence typing for 2554 genes in a large and heterogenous panel of 180 Listeria monocytogenes strains having diverse geographical and temporal origins.
Swarnali Louha   +2 more
doaj   +1 more source

Linkage Disequilibrium and Evaluation of Genome-Wide Association Mapping Models in Tetraploid Potato

open access: yesG3: Genes, Genomes, Genetics, 2018
Genome-wide association studies (GWAS) have become a powerful tool for analyzing complex traits in crop plants. The current study evaluates the efficacy of various GWAS models and methods for elucidating population structure in potato.
S. Sharma   +5 more
semanticscholar   +1 more source

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