Results 51 to 60 of about 127,775 (292)

A Data Driven Review of In Vitro Electrical and Mechanical Stimulation for Post‐Acute Phase Wound Healing

Advanced Healthcare Materials, EarlyView.
This review examines how in vitro electrical and mechanical stimulation modulates wound healing in fibroblasts and keratinocytes. Analyzing over 560 experimental data points, we relate stimulation parameters to proliferation and migration outcomes, evaluate platform designs, and highlight the need for multi‐parameter optimization to advance targeted ...
Matthew K. Burgess, Ellen F. Marsh, Veronica M. Lucian, Malavika Nair   +3 more
wiley   +1 more source

Relationship between NAFLD and coronary artery disease: A Mendelian randomization study

Hepatology, EarlyView., 2022
Abstract Background and Aims There is an ongoing debate on whether NAFLD is an active contributor or an innocent bystander in the pathogenesis of coronary artery disease (CAD). The aim of the present study was to assess the causal relationship between NAFLD and CAD.
Zhewen Ren, Pomme I. H. G. Simons, Anke Wesselius, Coen D. A. Stehouwer, Martijn C. G. J. Brouwers   +4 more
wiley   +1 more source

eQTL Meta‐Analysis Reveals Conserved and Population‐Specific Regulatory Variation Underlying Nutritional Trait Evolution and Domestication in Tomato

Advanced Science, EarlyView.
A comprehensive meta‐analysis of expression quantitative trait loci (eQTLs) across five diverse tomato populations reveals a high‐resolution atlas of transcriptional regulation and uncovers conserved and population‐specific regulatory architectures underlying fruit nutritional quality traits, including flavonoids, sugars, organic acids, carotenoids ...
Jiantao Zhao, Xin Wang, Jing Zhang, Ryan McQuinn, Je Min Lee, Itay Gonda, Ari Feder, Yimin Xu, Baike Wang, Qinghui Yu, Denise M. Tieman, Sanwen Huang, Harry Klee, James J. Giovannoni, Zhangjun Fei   +14 more
wiley   +1 more source

SOFTWARE FOR GENETIC MAPPING AND ANALYSIS OF MARKER/TRAIT ASSOCIATIONS

Овощи России, 2016
The paper presents the information about technical tools and software wide used for statistic calculations and detection of linkage disequilibrium marker/trait as well as association between traits/genes and molecular markers based on identification of ...
N. V. Kocherina, Yu. V. Chesnokov
doaj   +1 more source

Transmission/disequilibrium tests incorporating unaffected offspring. [PDF]

PLoS ONE, 2014
We propose a new method for family-based tests of association and linkage called transmission/disequilibrium tests incorporating unaffected offspring (TDTU).
Qinyu Wei, Yuanli Chen, Zheng Zeng, Chang Shu, Lu Long, Jianhua Lu, Yangxin Huang, Ping Yin   +7 more
doaj   +1 more source

Linkage score disequilibrium analysis results.

, 2023
Linkage score disequilibrium metrics for the three GWAS of the photoreceptor layers following analysis using LDSCore [20]. Metrics include lambda genomic control (GC), linkage disequilibrium score (LDSC) intercept and LDSC ratio. (PDF)
Ewan Birney (7728), Andrew R. Webster (8221650), Omar A. Mahroo (13844402), Tomas W. Fitzgerald (10789662), Praveen J. Patel (8027564), Anthony P. Khawaja (8770904), Hannah Currant (10789659)   +6 more
core   +1 more source

Natural Variation of NAR5 Determines Nitrogenase Activity and the Yield in Soybean

Advanced Science, EarlyView.
This study identified NAR5, a gene encoding a subtilisin‐like protease, that regulates nitrogenase activity in soybean nodules. Overexpressing NAR5 delayed nodule senescence, enhancing nitrogenase activity, yield, and low‐nitrogen tolerance. The elite haplotype NAR5HapI‐1 linked to superior nitrogenase activity and greater seed weight has been ...
Chao Ma, Hanyu Zhao, Haojie Feng, Xulun Dong, Lin Chen, Mingliang Yang, Runyi Chen, Chengjun Lei, Chunyan Liu, Qingshan Chen, Dawei Xin, Jinhui Wang   +11 more
wiley   +1 more source

Whole Genome Linkage Disequilibrium and Effective Population Size in a Coho Salmon (Oncorhynchus kisutch) Breeding Population Using a High-Density SNP Array

Frontiers in Genetics, 2019
The estimation of linkage disequilibrium between molecular markers within a population is critical when establishing the minimum number of markers required for association studies, genomic selection, and inferring historical events influencing different ...
Agustín Barría, Kris A. Christensen, Grazyella Yoshida, Ana Jedlicki, Jong S. Leong, Eric B. Rondeau, Jean P. Lhorente, Ben F. Koop, William S. Davidson, José M. Yáñez, José M. Yáñez   +10 more
doaj   +1 more source

Cross‐Modal Denoising and Integration of Spatial Multi‐Omics Data with CANDIES

Advanced Science, EarlyView.
In this paper, we introduce CANDIES, which leverages a conditional diffusion model and contrastive learning to effectively denoise and integrate spatial multi‐omics data. We conduct extensive evaluations on diverse synthetic and real datasets, CANDIES shows superior performance on various downstream tasks, including denoising, spatial domain ...
Ye Liu, Wanpeng Zou, Yuekai Li, Jiayi Wang, Mingxuan Cai, Hongmin Cai   +5 more
wiley   +1 more source

JLIN: A java based linkage disequilibrium plotter

BMC Bioinformatics, 2006
Background A great deal of effort and expense are being expended internationally in attempts to detect genetic polymorphisms contributing to susceptibility to complex human disease. Techniques such as Linkage Disequilibrium mapping are being increasingly
McCaskie Pamela A, Carter Kim W, Palmer Lyle J   +2 more
doaj   +1 more source