Disequilibrium linkage (gametic disequilibrium) of structural genes in the bovine population
In the population of Kholmogor cattle (n=824), gametic disequilibrium was studied for alleles of the polymorphic loci β-Lg (LGB), β-Cn (CSN2) and æ-Cn (CSN3). In purebred Kholmogor cattle, the β-casein polymorphism is determined by three alleles with the
V. S. Matyukov, V. G. Zainullin
doaj +1 more source
Extent of third-order linkage disequilibrium in a composite line of Iberian pigs
Background Previous studies on linkage disequilibrium have investigated second order linkage disequilibrium in animal and plant populations. The objective of this paper was to investigate the genome-wide levels of third order linkage disequilibrium in a ...
Luis Gomez-Raya +4 more
doaj +1 more source
Division of linkage disequilibrium between absolute linkage disequilibrium and linkage equilibrium [PDF]
Linkage disequilibrium is the association between alleles in the allele distributions across linked loci and is intermediate in character between the dependence and the independence of allele distribution. This ambivalence makes linkage disequilibrium difficult to understand and to treat mathematically.
openaire +2 more sources
Mapping genes through the use of linkage disequilibrium generated by genetic drift: 'Drift mapping' in small populations with no demographic expansion [PDF]
Linkage disequilibrium has been a powerful tool in identifying rare disease alleles in human populations. To date, most research has been directed to isolated populations which have undergone a bottleneck followed by rapid exponential expansion.
Zöllner, Sebastian +8 more
core +1 more source
Mendelian randomization makes use of genetic variants as instrumental variables to eliminate the influence induced by unknown confounders on causal estimation in epidemiology studies.
Yuquan Wang +5 more
doaj +1 more source
Short communication: Characterization of the genome-wide linkage disequilibrium in 2 divergent selection lines of dairy cows [PDF]
The objective of this study was to describe results of a genome-wide map of single nucleotide polymorphisms (SNP) and assess the linkage disequilibrium (LD) level in 2 divergent selection lines of dairy cows. DNA extracted from 299 Holstein cows was used
Coffey, M. P., Banos, G.
core +1 more source
Accurate Estimation of Effective Population Size in the Korean Dairy Cattle Based on Linkage Disequilibrium Corrected by Genomic Relationship Matrix [PDF]
Linkage disequilibrium between markers or genetic variants underlying interesting traits affects many genomic methodologies. In many genomic methodologies, the effective population size (Ne) is important to assess the genetic diversity of animal ...
Dong-Hyun Shin +4 more
doaj +1 more source
Confounding by linkage disequilibrium [PDF]
Linkage disequilibrium (LD) and confounding are two widely discussed concepts in Genetics and in Epidemiology, yet their relationship has received only intuitive or no considerations. Taken in the narrow sense, LD refers to the nonrandom association of alleles at two or more linked genetic loci.
openaire +2 more sources
Background Various software tools are available for the display of pairwise linkage disequilibrium across multiple single nucleotide polymorphisms. The HapMap project also presents these graphics within their website.
Day Ian NM +3 more
doaj +1 more source
Transient Linkage Disequilibrium in Drosophila
Uploaded by Plazi for TaxoDros. We do not have abstracts.
O'Brien, Stephen J., MacIntyre, Ross J.
openaire +4 more sources

