Results 31 to 40 of about 128,239 (292)

Transient Linkage Disequilibrium in Drosophila

Nature, 1971
Uploaded by Plazi for TaxoDros. We do not have abstracts.
O'Brien, Stephen J., MacIntyre, Ross J.
openaire   +4 more sources

Linkage score disequilibrium analysis results. [PDF]

, 2023
Linkage score disequilibrium metrics for the three GWAS of the photoreceptor layers following analysis using LDSCore [20]. Metrics include lambda genomic control (GC), linkage disequilibrium score (LDSC) intercept and LDSC ratio. (PDF)
Ewan Birney (7728), Andrew R. Webster (8221650), Omar A. Mahroo (13844402), Tomas W. Fitzgerald (10789662), Praveen J. Patel (8027564), Anthony P. Khawaja (8770904), Hannah Currant (10789659)   +6 more
core   +1 more source

A linkage disequilibrium-based approach to selecting disease-associated rare variants.

PLoS ONE, 2013
Rare variants have increasingly been cited as major contributors in the disease etiology of several complex disorders. Recently, several approaches have been proposed for analyzing the association of rare variants with disease.
Rajesh Talluri, Sanjay Shete
doaj   +1 more source

A web application to perform linkage disequilibrium and linkage analyses on a computational grid [PDF]

, 2009
Motivation: Unravelling the genetic architecture of complex traits requires large amounts of data, sophisticated models and large computational resources.
Hernandez Sanchez, Julio, Knott, S, Grunchec, J-A   +2 more
core   +1 more source

Genetic association mapping via evolution-based clustering of haplotypes. [PDF]

, 2007
Multilocus analysis of single nucleotide polymorphism haplotypes is a promising approach to dissecting the genetic basis of complex diseases. We propose a coalescent-based model for association mapping that potentially increases the power to detect ...
Ioanna Tachmazidou, Maria De Iorio, Claudio J. Verzilli, De Iorio, Maria, De Iorio, M, Claudio J Verzilli, Verzilli, Claudio J, Tachmazidou, I, Tachmazidou, Ioanna, Verzilli, CJ   +9 more
core   +1 more source

Linkage disequilibrium fine mapping of quantitative trait loci: A simulation study

Genetics Selection Evolution, 2003
Recently, the use of linkage disequilibrium (LD) to locate genes which affect quantitative traits (QTL) has received an increasing interest, but the plausibility of fine mapping using linkage disequilibrium techniques for QTL has not been well studied ...
Pérez-Enciso Miguel, Cierco-Ayrolles Christine, Goffinet Bruno, Abdallah Jihad M   +3 more
doaj   +1 more source

Multipoint linkage disequilibrium mapping using multilocus allele frequency data [PDF]

, 2005
This paper describes a likelihood based fine scale linkage disequilibrium mapping method for estimating the position of a disease predisposing gene relative to a battery of typed marker loci. The method uses multilocus allele frequency data from a sample
Johnson, T.
core   +1 more source

Characterization of genetic diversity and linkage disequilibrium of ZmLOX4 and ZmLOX5 loci in maize. [PDF]

PLoS ONE, 2013
Maize (Zea mays L.) lipoxygenases (ZmLOXs) are well recognized as important players in plant defense against pathogens, especially in cross kingdom lipid communication with pathogenic fungi.
Gerald N De La Fuente, Seth C Murray, Thomas Isakeit, Yong-Soon Park, Yuanxin Yan, Marilyn L Warburton, Michael V Kolomiets   +6 more
doaj   +1 more source

Does probabilistic modelling of linkage disequilibrium evolution improve the accuracy of QTL location in animal pedigree?

Genetics Selection Evolution, 2010
Background Since 2001, the use of more and more dense maps has made researchers aware that combining linkage and linkage disequilibrium enhances the feasibility of fine-mapping genes of interest.
Estivals Delphine, Ytournel Florence, Druet Tom, Gilbert Hélène, Legarra Andrés, Dejean Sébastien, Cierco-Ayrolles Christine, Oumouhou Naïma, Mangin Brigitte   +8 more
doaj   +1 more source

Whole genome genetic variation and linkage disequilibrium in a diverse collection of Listeria monocytogenes isolates.

PLoS ONE, 2021
We performed whole-genome multi-locus sequence typing for 2554 genes in a large and heterogenous panel of 180 Listeria monocytogenes strains having diverse geographical and temporal origins.
Swarnali Louha, Richard J Meinersmann, Travis C Glenn   +2 more
doaj   +1 more source