Results 31 to 40 of about 401,091 (199)

Bayesian estimates of linkage disequilibrium

BMC Genetics, 2007
Background The maximum likelihood estimator of D' – a standard measure of linkage disequilibrium – is biased toward disequilibrium, and the bias is particularly evident in small samples and rare haplotypes.
Abad-Grau María M, Sebastiani Paola
doaj   +1 more source

Linkage score disequilibrium analysis results.

, 2023
Linkage score disequilibrium metrics for the three GWAS of the photoreceptor layers following analysis using LDSCore [20]. Metrics include lambda genomic control (GC), linkage disequilibrium score (LDSC) intercept and LDSC ratio. (PDF)
Ewan Birney (7728), Andrew R. Webster (8221650), Omar A. Mahroo (13844402), Tomas W. Fitzgerald (10789662), Praveen J. Patel (8027564), Anthony P. Khawaja (8770904), Hannah Currant (10789659)   +6 more
core   +1 more source

Linkage disequilibrium fine mapping of quantitative trait loci: A simulation study

Genetics Selection Evolution, 2003
Recently, the use of linkage disequilibrium (LD) to locate genes which affect quantitative traits (QTL) has received an increasing interest, but the plausibility of fine mapping using linkage disequilibrium techniques for QTL has not been well studied ...
Pérez-Enciso Miguel, Cierco-Ayrolles Christine, Goffinet Bruno, Abdallah Jihad M   +3 more
doaj   +1 more source

Characterization of genetic diversity and linkage disequilibrium of ZmLOX4 and ZmLOX5 loci in maize. [PDF]

PLoS ONE, 2013
Maize (Zea mays L.) lipoxygenases (ZmLOXs) are well recognized as important players in plant defense against pathogens, especially in cross kingdom lipid communication with pathogenic fungi.
Gerald N De La Fuente, Seth C Murray, Thomas Isakeit, Yong-Soon Park, Yuanxin Yan, Marilyn L Warburton, Michael V Kolomiets   +6 more
doaj   +1 more source

Results of linkage disequilibrium analysis.

, 2022
Results of linkage disequilibrium analysis.
Mathilde Allegre (13919723), Gillian G. Bidaisee (13919720), Michel Boccara (121919), Duraisamy Saravanakumar (13919726), Olivier Fouet (121913), Xavier Argout (68581), Isaac Bekele (13919729), Frances L. Bekele (13919717), Claire Lanaud (121926)   +8 more
core   +1 more source

Does probabilistic modelling of linkage disequilibrium evolution improve the accuracy of QTL location in animal pedigree?

Genetics Selection Evolution, 2010
Background Since 2001, the use of more and more dense maps has made researchers aware that combining linkage and linkage disequilibrium enhances the feasibility of fine-mapping genes of interest.
Estivals Delphine, Ytournel Florence, Druet Tom, Gilbert Hélène, Legarra Andrés, Dejean Sébastien, Cierco-Ayrolles Christine, Oumouhou Naïma, Mangin Brigitte   +8 more
doaj   +1 more source

Whole genome genetic variation and linkage disequilibrium in a diverse collection of Listeria monocytogenes isolates.

PLoS ONE, 2021
We performed whole-genome multi-locus sequence typing for 2554 genes in a large and heterogenous panel of 180 Listeria monocytogenes strains having diverse geographical and temporal origins.
Swarnali Louha, Richard J Meinersmann, Travis C Glenn   +2 more
doaj   +1 more source

Association testing strategy for data from dense marker panels. [PDF]

PLoS ONE, 2013
Genome wide association studies have been usually analyzed in a univariate manner. The commonly used univariate tests have one degree of freedom and assume an additive mode of inheritance.
Donghyung Lee, Silviu-Alin Bacanu
doaj   +1 more source

SNP frequency, haplotype structure and linkage disequilibrium in elite maize inbred lines

BMC Genetics, 2002
Background Recent studies of ancestral maize populations indicate that linkage disequilibrium tends to dissipate rapidly, sometimes within 100 bp. We set out to examine the linkage disequilibrium and diversity in maize elite inbred lines, which have been
Smith Oscar, Dolan Maurine, Jung Mark, Caldwell Katherine S, Ching Ada, Tingey Scott, Morgante Michele, Rafalski Antoni J   +7 more
doaj   +1 more source

Highly localized divergence within supergenes in Atlantic cod (Gadus morhua) within the Gulf of Maine

BMC Genomics, 2017
Background Atlantic cod (Gadus morhua), is known to vary genetically across the North Atlantic, Greenland, and Newfoundland. This genetic variation occurs both spatially and temporally through decades of heavy fishing, and is concentrated in three ...
Bryan T. Barney, Christiane Munkholm, David R. Walt, Stephen R. Palumbi   +3 more
doaj   +1 more source