Results 41 to 50 of about 127,775 (292)
A linkage disequilibrium-based approach to selecting disease-associated rare variants.
PLoS ONE, 2013 Rare variants have increasingly been cited as major contributors in the disease etiology of several complex disorders. Recently, several approaches have been proposed for analyzing the association of rare variants with disease.
Rajesh Talluri, Sanjay Shete
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Genetic association mapping via evolution-based clustering of haplotypes. [PDF]
, 2007 Multilocus analysis of single nucleotide polymorphism haplotypes is a promising approach to dissecting the genetic basis of complex diseases. We propose a coalescent-based model for association mapping that potentially increases the power to detect ...
Ioanna Tachmazidou +9 more
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Linkage disequilibrium fine mapping of quantitative trait loci: A simulation study
Genetics Selection Evolution, 2003 Recently, the use of linkage disequilibrium (LD) to locate genes which affect quantitative traits (QTL) has received an increasing interest, but the plausibility of fine mapping using linkage disequilibrium techniques for QTL has not been well studied ...
Pérez-Enciso Miguel +3 more
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Characterization of genetic diversity and linkage disequilibrium of ZmLOX4 and ZmLOX5 loci in maize. [PDF]
PLoS ONE, 2013 Maize (Zea mays L.) lipoxygenases (ZmLOXs) are well recognized as important players in plant defense against pathogens, especially in cross kingdom lipid communication with pathogenic fungi.
Gerald N De La Fuente +6 more
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Genetics Selection Evolution, 2010 Background Since 2001, the use of more and more dense maps has made researchers aware that combining linkage and linkage disequilibrium enhances the feasibility of fine-mapping genes of interest.
Estivals Delphine +8 more
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PLoS ONE, 2021 We performed whole-genome multi-locus sequence typing for 2554 genes in a large and heterogenous panel of 180 Listeria monocytogenes strains having diverse geographical and temporal origins.
Swarnali Louha +2 more
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Association testing strategy for data from dense marker panels. [PDF]
PLoS ONE, 2013 Genome wide association studies have been usually analyzed in a univariate manner. The commonly used univariate tests have one degree of freedom and assume an additive mode of inheritance.
Donghyung Lee, Silviu-Alin Bacanu
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SNP frequency, haplotype structure and linkage disequilibrium in elite maize inbred lines
BMC Genetics, 2002 Background Recent studies of ancestral maize populations indicate that linkage disequilibrium tends to dissipate rapidly, sometimes within 100 bp. We set out to examine the linkage disequilibrium and diversity in maize elite inbred lines, which have been
Smith Oscar +7 more
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BMC Genomics, 2017 Background Atlantic cod (Gadus morhua), is known to vary genetically across the North Atlantic, Greenland, and Newfoundland. This genetic variation occurs both spatially and temporally through decades of heavy fishing, and is concentrated in three ...
Bryan T. Barney +3 more
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