Results 41 to 50 of about 387,849 (295)

Linkage disequilibrium.

, 2016
Linkage disequilibrium.
Farzaneh Dehghan (3339984), Ric N. Price (35538), Hidayat Trimarsanto (443615), Yaghoob Hamedi (3339978), Sheren To (814157), Khojasteh Sharifi-Sarasiabi (3339975), Reza Safari (3339981), Irene Handayuni (3141168), Sarah Auburn (106239)   +8 more
core   +2 more sources

Highly localized divergence within supergenes in Atlantic cod (Gadus morhua) within the Gulf of Maine

BMC Genomics, 2017
Background Atlantic cod (Gadus morhua), is known to vary genetically across the North Atlantic, Greenland, and Newfoundland. This genetic variation occurs both spatially and temporally through decades of heavy fishing, and is concentrated in three ...
Bryan T. Barney, Christiane Munkholm, David R. Walt, Stephen R. Palumbi   +3 more
doaj   +1 more source

Linkage disequilibrium and recombination rate estimates in the self-incompatibility region of Arabidopsis lyrata [PDF]

, 2007
Genetic diversity is unusually high at loci in the S-locus region of the self-incompatible species of the flowering plant, Arabidopsis lyrata, not just in the S loci themselves, but also at two nearby loci.
Deborah Charlesworth, Esther Kamau, Charlesworth, Brian, Brian Charlesworth, Kamau, Esther, Charlesworth, Deborah   +5 more
core   +1 more source

Integrative Omics Analysis Reveals the Regulation of Hypoxia Tolerance in Large Yellow Croaker (Larimichthys crocea) via the Lipoic Acid Synthase (lias) Gene

Advanced Science, EarlyView.
Lipoic acid synthase (lias) can regulate α‐KG levels through lipoylation, thereby negatively regulating HIF‐1α protein levels via PHD under hypoixa. The Hap2 allele of lias exhibits lower expression levels than Hap1, leading to the accumulation of more HIF‐1α protein and thereby enhancing hypoxia tolerance. ABSTRACT Hypoxia stress seriously affects the
Jie Ding, Songpeng Jia, Ran Meng, Xuelei Wang, Xiongfei Wu, Weiliang Shen, Yibo Zhang, Junquan Zhu   +7 more
wiley   +1 more source

Linkage Disequilibrium and Effective Population Size of Buffalo Populations of Iran, Turkey, Pakistan, and Egypt Using a Medium Density SNP Array

Frontiers in Genetics, 2021
Linkage disequilibrium (LD) across the genome provides information to identify the genes and variations related to quantitative traits in genome-wide association studies (GWAS) and for the implementation of genomic selection (GS).
Shirin Rahimmadar, Mokhtar Ghaffari, Mahdi Mokhber, John L. Williams, John L. Williams   +4 more
doaj   +1 more source

Whole‐Genome Sequencing Pilot of the Central Asian Genomic Diversity Project Reveals Distinct Histories, Adaptation, and Introgression

Advanced Science, EarlyView.
As a pilot phase of the Central Asian Genomic Diversity Project, whole‐genome sequencing of 166 individuals from 20 Central Asian and Afghan Hazara populations reveals fine‐scale substructure shaped by repeated trans‐Eurasian migration and admixture. Integrated analyses uncover post‐admixture adaptation, archaic introgression, and medically relevant ...
Mengge Wang, Shuhan Duan, Qiuxia Sun, Renkuan Tang, Lintao Luo, Jie Zhong, Zhaxylyk Sabitov, CAGDP Consortium†, Lan‐Hai Wei, Chao Liu, Maxat Zhabagin, Guanglin He   +11 more
wiley   +1 more source

SOFTWARE FOR GENETIC MAPPING AND ANALYSIS OF MARKER/TRAIT ASSOCIATIONS

Овощи России, 2016
The paper presents the information about technical tools and software wide used for statistic calculations and detection of linkage disequilibrium marker/trait as well as association between traits/genes and molecular markers based on identification of ...
N. V. Kocherina, Yu. V. Chesnokov
doaj   +1 more source

Transmission/disequilibrium tests incorporating unaffected offspring. [PDF]

PLoS ONE, 2014
We propose a new method for family-based tests of association and linkage called transmission/disequilibrium tests incorporating unaffected offspring (TDTU).
Qinyu Wei, Yuanli Chen, Zheng Zeng, Chang Shu, Lu Long, Jianhua Lu, Yangxin Huang, Ping Yin   +7 more
doaj   +1 more source

Harnessing Large‐Scale Multi‐Omics Data for Risk Prediction and Deep Phenotyping of Valvular Heart Diseases in the General Population

Advanced Science, EarlyView.
Large‐scale UK Biobank analyses identify clinical and proteomic signatures for early prediction of valvular heart disease and its subtypes. Proteins add predictive value for VHD, AVS, and MVR, with outcome‐specific compact panels showing translational potential. Multi‐layer evidence highlights matrix remodeling, protease regulation, immune inflammation,
Zhihao Jiang, Yang Liu, Mingyu Song, Ning Chen, Canqing Yu, Jun Lv, Eric Yuk Fai Wan, Lu Qi, Liming Li, Dianjianyi Sun, Bang Zheng   +10 more
wiley   +1 more source

JLIN: A java based linkage disequilibrium plotter

BMC Bioinformatics, 2006
Background A great deal of effort and expense are being expended internationally in attempts to detect genetic polymorphisms contributing to susceptibility to complex human disease. Techniques such as Linkage Disequilibrium mapping are being increasingly
McCaskie Pamela A, Carter Kim W, Palmer Lyle J   +2 more
doaj   +1 more source