Results 21 to 30 of about 401,091 (199)
Division of linkage disequilibrium between absolute linkage disequilibrium and linkage equilibrium [PDF]
Journal of Human Genetics, 2005 Linkage disequilibrium is the association between alleles in the allele distributions across linked loci and is intermediate in character between the dependence and the independence of allele distribution. This ambivalence makes linkage disequilibrium difficult to understand and to treat mathematically.
openaire +2 more sources
Short communication: Characterization of the genome-wide linkage disequilibrium in 2 divergent selection lines of dairy cows [PDF]
, 2010 The objective of this study was to describe results of a genome-wide map of single nucleotide polymorphisms (SNP) and assess the linkage disequilibrium (LD) level in 2 divergent selection lines of dairy cows. DNA extracted from 299 Holstein cows was used
Coffey, M. P. +3 more
core +1 more source
Frontiers in Genetics, 2021 Mendelian randomization makes use of genetic variants as instrumental variables to eliminate the influence induced by unknown confounders on causal estimation in epidemiology studies.
Yuquan Wang +5 more
doaj +1 more source
Accurate Estimation of Effective Population Size in the Korean Dairy Cattle Based on Linkage Disequilibrium Corrected by Genomic Relationship Matrix [PDF]
Asian-Australasian Journal of Animal Sciences, 2013 Linkage disequilibrium between markers or genetic variants underlying interesting traits affects many genomic methodologies. In many genomic methodologies, the effective population size (Ne) is important to assess the genetic diversity of animal ...
Dong-Hyun Shin +4 more
doaj +1 more source
Cosmopolitan linkage disequilibrium maps
Human Genomics, 2005 Linkage maps have been invaluable for the positional cloning of many genes involved in severe human diseases. Standard genetic linkage maps have been constructed for this purpose from the Centre d'Etude du Polymorphisme Humain and other panels, and have ...
Gibson Jane +4 more
doaj +1 more source
Confounding by linkage disequilibrium [PDF]
Journal of Human Genetics, 2013 Linkage disequilibrium (LD) and confounding are two widely discussed concepts in Genetics and in Epidemiology, yet their relationship has received only intuitive or no considerations. Taken in the narrow sense, LD refers to the nonrandom association of alleles at two or more linked genetic loci.
openaire +2 more sources
BMC Bioinformatics, 2006 Background Various software tools are available for the display of pairwise linkage disequilibrium across multiple single nucleotide polymorphisms. The HapMap project also presents these graphics within their website.
Day Ian NM +3 more
doaj +1 more source
Transient Linkage Disequilibrium in Drosophila
Nature, 1971 Uploaded by Plazi for TaxoDros. We do not have abstracts.
O'Brien, Stephen J., MacIntyre, Ross J.
openaire +4 more sources
A linkage disequilibrium-based approach to selecting disease-associated rare variants.
PLoS ONE, 2013 Rare variants have increasingly been cited as major contributors in the disease etiology of several complex disorders. Recently, several approaches have been proposed for analyzing the association of rare variants with disease.
Rajesh Talluri, Sanjay Shete
doaj +1 more source