Results 131 to 140 of about 1,573,513 (310)
Metastatic niche shaped by host factors influences disseminated cancer cell fate
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward +2 more
wiley +1 more source
Linkage mapping of quantitative trait loci in humans: an overview
In this article, we provide an overview of the different statistical procedures that have been developed for linkage mapping of quantitative trait loci. We outline the model assumptions, the data requirements and the underlying tests for linkage for the ...
Majumder, P. P., Ghosh, S., Reich, T.
core +1 more source
Lysyl oxidase (LOX)‐mediated remodeling of the extracellular matrix
The lysyl oxidase (LOX) family of enzymes drives extracellular matrix remodeling by oxidizing collagen, elastin, and fibronectin, promoting covalent cross‐link formation. This activity regulates tissue architecture and mechanical properties, while its dysregulation contributes to fibrosis, cardiovascular disease, glaucoma, connective tissue disorders ...
Fernando Rodríguez‐Pascual +3 more
wiley +1 more source
Urandangi, Queensland [cartographic material] /
1st ed. Topographic map of Urandangi region, Queensland, showing classes of roads, railway and telephone lines, fences, state boundries, watercourses and dams, windpumps, and bore, tank and well classifictions. Relief shown by hachures and spot heights.;
Australia. National Mapping Section.
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Detection of growth-related QTLs in turbot (Scophtalmus maximux) [PDF]
Background The turbot (Scophthalmus maximus) is a highly appreciated European aquaculture species. Growth related traits constitute the main goal of the ongoing genetic breeding programs of this species. The recent construction of a consensus linkage map
Toro Ibañez, Miguel Angel +8 more
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Smaller is better: nanobodies meet NMR
Nanobodies are single‐domain antigen‐binding fragments derived from camelid heavy chain antibodies. Their small size, high stability, and exceptional specificity make nanobodies uniquely useful probes for NMR studies of protein dynamics, transient conformational states, and protein–protein interactions.
Oleg Y. Dmitriev
wiley +1 more source
Avon Downs, Northern Territory [cartographic material] /
1st ed. Topographic map of Avon Downs region, Northern Territory, showing classes of roads, railway and telephone lines, fences, state boundries, watercourses and dams, windpumps, and bore, tank and well classifictions.
Australia. National Mapping Section.
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Transient oligomers formed by intrinsically disordered proteins may be ‘invisible’ to direct detection yet remain accessible to solution NMR through equilibrium‐exchange measurements and pressure‐jump experiments. Complementary methods report on mass, stoichiometry, selected distance distributions, morphology, and internal packing.
Martin D. Gelenter, Ad Bax
wiley +1 more source
Neutralization of the PTX3/CD44 axis suppresses TGF‐β1 signaling in kidney fibrosis
This study investigates how the PTX3/CD44 axis promotes kidney fibrosis by activating TGF‐β1 signaling. We demonstrate that the neutralizing antibody WHC‐001 effectively inhibits this pathway, suppressing myofibroblast activation and partial epithelial–mesenchymal transition (EMT).
Chao‐Chun Cheng +8 more
wiley +1 more source
Tasmania 1:25 000 series [cartographic material] /
Topographic map series with cadastral information. Relief shown by contours and spot heights. Depths shown by soundings.; "Tasmap."; Sheets of various eds.; Some sheets are issued by: Mapping Division, Department of Lands, Parks and Wildlife; Mapping ...
Tasmania. Lands Department Mapping Division.
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