Results 161 to 170 of about 392,493 (302)

Genetic linkage mapping in Megathyrsus maximus (Jacq.) with multiple dosage markers. [PDF]

G3 (Bethesda)
Gesteira GS, Ferreira GC, Mollinari M, Santos MF, Jank L, Vilela MM, Raposo A, Chiari L, Zeng ZB, Garcia AAF.   +9 more
europepmc   +1 more source

An Integration of Linkage Mapping and GWAS Reveals the Key Genes for Ear Shank Length in Maize. [PDF]

Int J Mol Sci, 2022
Liang Z, Xi N, Liu H, Liu P, Xiang C, Zhang C, Zou C, Cheng X, Yu H, Zhang M, Chen Z, Pan G, Yuan G, Gao S, Ma L, Shen Y.   +15 more
europepmc   +1 more source

Dual PI3K/AKT and CDK4/6 inhibition reveals selective sensitivity in an SHH medulloblastoma stem cell model

Molecular Oncology, EarlyView.
Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute, Madeleine Birgersson, Paolo Ceriani, Margareta Wilhelm, Ourania N Kostopoulou   +4 more
wiley   +1 more source

Linkage Disequilibrium Mapping [PDF]

, 2020
openaire   +2 more sources

Avirulence genes identified through linkage mapping and region-specific association studies in the wheat leaf rust pathogen Puccinia triticina. [PDF]

BMC Genomics
Liu L, Formby S, Kim SH, Joly DL, Mulock B, Lubberts M, Saville B, McCallum B, Bakkeren G.   +8 more
europepmc   +1 more source

High-density linkage mapping and genetic dissection of resistance to broomrape (Orobanche crenata Forsk.) in pea (Pisum sativum L.). [PDF]

Front Plant Sci, 2023
Delvento C, Arcieri F, Marcotrigiano AR, Guerriero M, Fanelli V, Dellino M, Curci PL, Bouwmeester H, Lotti C, Ricciardi L, Pavan S.   +10 more
europepmc   +1 more source

Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer

Molecular Oncology, EarlyView.
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni, Antonella Palmese, Stefano Scalera, Laura Cipriani, Davide Mascolo, Patrizia Vici, Teresa Arcuri, Lorena Filomeno, Eriseld Krasniqi, Giovanni Blandino, Giulia Bon, Marcello Maugeri‐Saccà   +11 more
wiley   +1 more source

Integrating linkage mapping and GWAS reveals novel genetic architecture of seed weight in soybean (<i>Glycine max</i> L.). [PDF]

Front Plant Sci
Zhang C, Hong H, Yuan R, Zhao K, Zha B, Lamlom SF, Xi X, Ren H, Qiu L, Wang J.   +9 more
europepmc   +1 more source

Identification of candidate genes for salinity tolerance in Japonica rice at the seedling stage based on genome-wide association study and linkage mapping. [PDF]

Front Plant Sci, 2023
Xu S, Cui J, Cao H, Liang S, Ma T, Liu H, Wang J, Yang L, Xin W, Jia Y, Zou D, Zheng H.   +11 more
europepmc   +1 more source

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

Molecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova, Michele Montrone, Uday Rangaswamy, Francesco Diversi, Irene Schiavo, Denise Ferrarini, Roberta Di Florio, Irene Longo, Michele Coscia, Nicola Zamboni, Giorgia Demontis, Lisa Veghini, Vincenzo Corbo, Remo Sanges, Paul Heppenstall   +14 more
wiley   +1 more source