Results 181 to 190 of about 392,493 (302)

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

Molecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu, Xixi Lin, Emil Mladenov, Veronika Mladenova, Jürgen Thomale, Ali Sak, Yao Wang, Yunxuan Deng, Eleni Gkika, Martin Stuschke, George Iliakis   +10 more
wiley   +1 more source

Genome-wide association analysis and linkage mapping decipher the genetic control of primary metabolites and quality traits in Capsicum. [PDF]

Plant J
von Steimker J, Wendenburg R, Klemmer A, Rosaria M, Fernie AR, Alseekh S, Tripodi P.   +6 more
europepmc   +1 more source

Linkage mapping and association analysis to identify a reliable QTL for stigma exsertion rate in rice. [PDF]

Front Plant Sci, 2022
Liu Y, Fu D, Kong D, Ma X, Zhang A, Wang F, Wang L, Xia H, Liu G, Yu X, Luo L.   +10 more
europepmc   +1 more source

LINKAGE MAPS IN CHLAMYDOMONAS REINHARDI [PDF]

Genetics, 1962
W T, EBERSOLD, R P, LEVINE, E E, LEVINE, M A, OLMSTED   +3 more
openaire   +2 more sources

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

Molecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

SNP-based linkage mapping reveals novel quantitative trait loci for yield traits in noug (<i>Guizotia abyssinica</i> (L. f.) Cass.). [PDF]

Front Plant Sci
Gebeyehu A, Hammenhag C, Vetukuri RR, Ortiz R, Geleta M.   +4 more
europepmc   +1 more source

Linkage mapping and QTL analysis of growth traits in Rhopilema esculentum. [PDF]

Sci Rep, 2022
Chen B, Li Y, Tian M, Su H, Sun W, Li Y.
europepmc   +1 more source

NKCC1: A key regulator of glioblastoma progression

Molecular Oncology, EarlyView.
Glioblastoma (GBM) progression is driven by disrupted chloride cotransporter homeostasis. NKCC1 is highly expressed in stem‐like, astrocytic, and progenitor cells, correlating with earlier recurrence, while overall survival remains unaffected. NKCC1 serves as a prognostic marker and potential therapeutic target, linking chloride transporter imbalance ...
Anja Thomsen, Diana Freitag, Madlen Haase, Christian Senft, Falko Schwarz, Silke Keiner   +5 more
wiley   +1 more source

Genome-wide association study, linkage mapping and transcriptomic analysis revealed candidate genes with the flag leaf traits associated with nitrogen use efficiency in wheat. [PDF]

BMC Genomics
Jia Y, Xu N, Wu J, Wang C, Huang M, Li Y.   +5 more
europepmc   +1 more source

Integrating Association Mapping, Linkage Mapping, Fine Mapping with RNA Seq Conferring Seedling Vigor Improvement for Successful Crop Establishment in Deep Sown Direct-Seeded Rice. [PDF]

Rice (N Y), 2023
Sandhu N, Ankush AP, Singh J, Raigar OP, Bains S, Jindal T, Singh MP, Sethi M, Pruthi G, Augustine G, Verma VK, Goyal S, Kumar A, Panwar H, Sihag MK, Kaur R, Kurup S, Kumar A.   +17 more
europepmc   +1 more source