Results 121 to 130 of about 3,557,497 (332)

Visualizing Linked Open Data

open access: yes, 2013
A query language called SPARQL has been developed to extract knowledge from Linked Data. Composing a SPARQL query is still mainly for the technical savvy. To expose the potential of Linked Data to other less-technical domains, novel visualization techniques are essential.
Waagmeester, Andra   +2 more
openaire   +1 more source

Imeglimin attenuates liver fibrosis by inhibiting vesicular ATP release from hepatic stellate cells

open access: yesFEBS Letters, EarlyView.
Imeglimin, at clinically relevant concentrations, inhibits vesicular ATP accumulation and release from hepatic stellate cells, thereby attenuating purinergic signaling and reducing fibrogenic activation. This mechanism reveals a newly identified antifibrotic action of imeglimin beyond glycemic control.
Seiji Nomura   +8 more
wiley   +1 more source

Semantic Enrichment of a Multilingual Archive with Linked Open Data [PDF]

open access: yes, 2017
This paper introduces MERCKX, a Multilingual Entity/Resource Combiner & Knowledge eXtractor. A case study involving the semantic enrichment of a multilingual archive is presented with the aim of assessing the relevance of natural language processing ...
De Wilde, Max, Hengchen, Simon
core  

Revealing the structure of land plant photosystem II: the journey from negative‐stain EM to cryo‐EM

open access: yesFEBS Letters, EarlyView.
Advances in cryo‐EM have revealed the detailed structure of Photosystem II, a key protein complex driving photosynthesis. This review traces the journey from early low‐resolution images to high‐resolution models, highlighting how these discoveries deepen our understanding of light harvesting and energy conversion in plants.
Roman Kouřil
wiley   +1 more source

Representing Dataset Quality Metadata using Multi-Dimensional Views

open access: yes, 2014
Data quality is commonly defined as fitness for use. The problem of identifying quality of data is faced by many data consumers. Data publishers often do not have the means to identify quality problems in their data.
Auer, Sören   +2 more
core   +1 more source

RAD50 missense variants differentially affect the DNA damage response and mitotic progression

open access: yesFEBS Letters, EarlyView.
RAD50 incorporates into the MRN complex and initiates the DNA damage response. Furthermore, RAD50 promotes mitotic progression. RAD50 missense variants capable of forming an MRN complex supported the DNA damage response and mitotic features to different extents in complementation experiments, indicating these functions are separable and might impact ...
Hanna Redeker   +9 more
wiley   +1 more source

Mapping the evolution of mitochondrial complex I through structural variation

open access: yesFEBS Letters, EarlyView.
Respiratory complex I (CI) is crucial for bioenergetic metabolism in many prokaryotes and eukaryotes. It is composed of a conserved set of core subunits and additional accessory subunits that vary depending on the organism. Here, we categorize CI subunits from available structures to map the evolution of CI across eukaryotes. Respiratory complex I (CI)
Dong‐Woo Shin   +2 more
wiley   +1 more source

A Study of Linked Open Data Life Cycles [PDF]

open access: yes, 2017
Artigo apresentado no I Workshop de Informação, Dados e Tecnologia, realizado entre nos dias 04 e 06 de setembro de 2017, na cidade de Florianópolis (SC), no Auditório do Espaço Físico Integrado (EFI) da Universidade Federal de Santa Catarina (UFSC ...
Gomes, Murilo Silveira   +2 more
core  

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

open access: yesFEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi   +5 more
wiley   +1 more source

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