Results 61 to 70 of about 1,768,814 (253)
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
FEBS Letters, EarlyView.This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva +5 more
wiley +1 more source
Using SPARQL to access Linked Open Data
The Programming Historian, 2015 This lesson explains why many cultural institutions are adopting graph databases, and how researchers can access these data though the query language called SPARQL.
Matthew Lincoln
doaj
, 2007 Paul Miller, Linked Data - the real Semantic Web? <em> Nodalities </em> , May 22, 2007. (Thanks to Peter Murray-Rust.)
openaire +1 more source
FEBS Letters, EarlyView.The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source
Von der Schneeflocke zur Lawine: Möglichkeiten der Nutzung freier Zitationsdaten in Bibliotheken
o-bib. Das offene Bibliotheksjournal, 2017 Zitationen spielen eine wichtige Rolle im wissenschaftlichen Diskurs, in der Recherchepraxis sowie im Bereich der Bibliometrie. In jüngster Zeit gibt es zunehmend Initiativen, die Zitationen als Open Data zur freien Nachnutzung verfügbar machen.
Annette Klein
doaj +1 more source
FEBS Letters, EarlyView.We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
wiley +1 more source
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
Linked Open Government Data: Still a Viable Option for Sharing and Integrating Public Data?
Future InternetLinked Data (LD) principles, when applied to Open Government Data (OGD), aim to make government data accessible and interconnected, unlocking its full potential and facilitating widespread reuse.
Alfonso Quarati, Riccardo Albertoni
doaj +1 more source
FEBS Letters, EarlyView.In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai +9 more
wiley +1 more source