Results 21 to 30 of about 4,236,805 (394)

Nucleus-specific linker histones Hho1 and Mlh1 form distinct protein interactions during growth, starvation and development in Tetrahymena thermophila [PDF]

open access: yes, 2019
Chromatin organization influences most aspects of gene expression regulation. The linker histone H1, along with the core histones, is a key component of eukaryotic chromatin.
Pearlman, Ronald E.   +7 more
core   +1 more source

Design, Synthesis and Evaluation of N-pyrazinylbenzamides as Potential Antimycobacterial Agents

open access: yesMolecules, 2018
Three series of N-(pyrazin-2-yl)benzamides were designed as retro-amide analogues of previously published N-phenylpyrazine-2-carboxamides with in vitro antimycobacterial activity. The synthesized retro-amides were evaluated for in vitro growth inhibiting
Jan Zitko   +7 more
doaj   +1 more source

Thiol-Reactive PODS-Bearing Bifunctional Chelators for the Development of EGFR-Targeting [18F]AlF-Affibody Conjugates

open access: yesMolecules, 2020
Site-selective bioconjugation of cysteine-containing peptides and proteins is currently achieved via a maleimide–thiol reaction (Michael addition).
Chiara Da Pieve   +5 more
doaj   +1 more source

Protective Efficacy of Recombinant Influenza Hemagglutinin Ectodomain Fusions

open access: yesViruses, 2021
In current seasonal influenza vaccines, neutralizing antibody titers directed against the hemagglutinin surface protein are the primary correlate of protection. These vaccines are, therefore, quantitated in terms of their hemagglutinin content.
Nidhi Mittal   +9 more
doaj   +1 more source

RECONSTITUTION OF ALLOPHYCOCYANIN FROM Mastigocladus laminosus WITH ISOLATED LINKER POLYPEPTIDE [PDF]

open access: yes, 1993
The core linker polypeptide Lc 8.9 was isolated from Mastigocladus laminosus and purified on a preparative scale. A method for the reconstitution of allophycocyanin (AP)—linker complexes from isolated polypeptides was developed. The complex (αAP(βAP)3 Lc
Gottschalk, Lothar   +2 more
core   +1 more source

Strategies for Expressing Possession in Some Iranian Linguistic Varieties [PDF]

open access: yesمطالعات زبان‌‌ها و گویش‌های غرب ایران, 2019
The present study aims at reviewing the strategies employed in some Iranian linguistic varieties in order to express possession. To do so, first the type of possessive strategy used in each variety was described based upon the categorization made by ...
Shahla Sharifi, Narjes Banoo Sabouri
doaj   +1 more source

A versatile characterization of poly(N-isopropylacrylamideco- N,N'-methylene-bis-acrylamide) hydrogels for composition, mechanical strength, and rheology [PDF]

open access: yes, 2013
Poly(N-isopropylacrylamide-co-N,N"-methylene-bisacrylamide) (P(NIPAAm-co-MBA)) hydrogels were prepared in water using redox initiator. The copolymer composition at high conversion (> 95%) was determined indirectly by HPLC (high performance liquid ...
Chetty, A.   +7 more
core   +1 more source

Blockade of Human α7 Nicotinic Acetylcholine Receptor by α-Conotoxin ImI Dendrimer: Insight from Computational Simulations

open access: yesMarine Drugs, 2019
Nicotinic acetylcholine receptors (nAChRs) are ligand-gated ion channels that are involved in fast synaptic transmission and mediated physiological activities in the nervous system.
Xiaoxiao Xu   +4 more
doaj   +1 more source

Antibody–Drug Conjugates: The Last Decade

open access: yesPharmaceuticals, 2020
An armed antibody (antibody–drug conjugate or ADC) is a vectorized chemotherapy, which results from the grafting of a cytotoxic agent onto a monoclonal antibody via a judiciously constructed spacer arm.
Nicolas Joubert   +3 more
doaj   +1 more source

Functionalization of Iron Nanoparticles with Linkers for Removal of Pollutants in Water [PDF]

open access: yesWater Harvesting Research, 2022
Today, quality monitoring of water resources played an influential role in its exploitation and use. Water sources usually contain heavy metals in minor concentrations.
Raziyeh Shamshirgaran   +3 more
doaj   +1 more source

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